A kind of compound oral ulcer patch and preparation method thereof

A technology for oral ulcers and sticking films, which is applied in the field of medicine and can solve problems such as poor effect and long treatment cycle

Active Publication Date: 2021-06-25
河南护理职业学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The invention provides a compound oral ulcer film and its preparation method, which solves the problems that the existing oral ulcer film has only one layer of medicine and only treats the ulcer, the effect is not good, and the treatment period is long.

Method used

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  • A kind of compound oral ulcer patch and preparation method thereof
  • A kind of compound oral ulcer patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A compound oral ulcer plaster, comprising a myogenic layer, a slow-release layer and a heat-clearing and antibacterial layer, the said myogenic layer includes a film-forming material, a plasticizer, a softener and a muscle-inducing drug, and said slow-release layer includes a forming Film materials, plasticizers and softeners, the heat-clearing and antibacterial layer includes film-forming materials, slow-release components, and heat-clearing and antibacterial drug components.

[0030]The myogenic layer includes 75 parts by weight of film-forming material, 2 parts of plasticizer, 3 parts of solvent softener, and 20 parts of myogenic medicine. 5 parts of pearl powder, 1 part of catechu water extract, 2 parts of astragalus water extract and 2 parts of borneol.

[0031] Cornus officinalis water extract, catechu water extract and Astragalus membranaceus water extract were respectively used at a solid-liquid ratio of 1g:5ml, decocted with water for 2 hours, filtered, and dri...

Embodiment 2

[0043] A compound oral ulcer plaster, comprising a myogenic layer, a slow-release layer and a heat-clearing and antibacterial layer, the said myogenic layer includes a film-forming material, a plasticizer, a softener and a muscle-inducing drug, and said slow-release layer includes a forming Film materials, plasticizers and softeners, the heat-clearing and antibacterial layer includes film-forming materials, slow-release components, and heat-clearing and antibacterial drug components.

[0044] The myogenic layer includes 80 parts by weight of film-forming materials, 3 parts of plasticizers, 4 parts of solvent softeners, and 15 parts of myogenic drugs. 1 part, 4 parts of pearl powder, 2 parts of water extract of catechu, 1 part of water extract of Astragalus membranaceus and 2 parts of borneol. Cornus officinalis water extract, catechu water extract and Astragalus membranaceus water extract were respectively used at a solid-liquid ratio of 1g:5ml, decocted with water for 2 hours...

Embodiment 3

[0056] A compound oral ulcer plaster, comprising a myogenic layer, a slow-release layer and a heat-clearing and antibacterial layer, the said myogenic layer includes a film-forming material, a plasticizer, a softener and a muscle-inducing drug, and said slow-release layer includes a forming Film materials, plasticizers and softeners, the heat-clearing and antibacterial layer includes film-forming materials, slow-release components, and heat-clearing and antibacterial drug components.

[0057] The myogenic layer includes 85 parts by weight of film-forming materials, 2.5 parts of plasticizers, 4 parts of solvent softeners, and 10 parts of myogenic drugs. 1 part, 3 parts of pearl powder, 1 part of water extract of catechu, 1 part of water extract of Astragalus membranaceus and 3 parts of borneol.

[0058] Cornus officinalis water extract, catechu water extract and Astragalus membranaceus water extract were respectively used at a solid-liquid ratio of 1g:5ml, decocted with water f...

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Abstract

The invention relates to a compound oral ulcer patch and a preparation method thereof, comprising a muscle-generating layer, a slow-release layer and a heat-clearing and antibacterial layer, and the muscle-generating layer includes a film-forming material, a plasticizer, a solvent softener, and a muscle-generating drug , the slow-release layer includes a film-forming material, a plasticizer and a softener, and the heat-clearing and antibacterial layer includes a film-forming material, a sustained-release component, and a heat-clearing and antibacterial drug component. The invention adopts a three-layer composite structure, the myogenic layer is in contact with the ulcer site, and mainly adopts muscle-inducing drugs to promote rapid muscle growth and repair of the ulcer; the heat-clearing and antibacterial layer mainly uses heat-clearing and antibacterial drugs for clearing away heat and killing Bacteria mainly provide a good environment for the recovery of ulcers. The slow-release layer uses bletilla striata polysaccharide or chitosan, which mainly prevents the saliva from dissolving the myogenic layer after the heat-clearing and antibacterial layer is dissolved. The three-layer structure can effectively improve the oral environment and at the same time make the ulcer site recover quickly.

Description

technical field [0001] The invention relates to a compound oral ulcer patch and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] Oral ulcer, also known as recurrent oral ulcer, aphtha, etc., is a common oral mucosal disease with spontaneous and recurrent. Ulcers are often found in buccal mucosa, lip mucosa, tongue and other parts. They are round or oval ulcers with obvious edges. The ulcer surface is covered with light yellowish white or grayish yellow cellulose derivatives. Two to 48 hours after the ulcer occurred, a characteristic prodromal burning sensation appeared, which seriously affected the patient's eating. The etiology of oral ulcers is complex, resulting in the diversity and uncertainty of its treatment methods. Clinically, symptomatic treatment is mostly used, usually from reducing inflammation, relieving pain, preventing ulcer surface deterioration, preventing secondary infection, and promoting healing. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/70A61K36/481A61K36/8968A61K47/36A61P1/02A61K35/618A61K31/045A61K31/715A61K31/722
CPCA61K9/006A61K9/7007A61K31/045A61K31/715A61K31/722A61K35/618A61K36/19A61K36/344A61K36/40A61K36/48A61K36/481A61K36/484A61K36/634A61K36/744A61K36/8968A61K47/36A61K2236/331A61K2236/51A61P1/02A61K2300/00
Inventor 付娟刘瑞红李娜石娟
Owner 河南护理职业学院
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