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Epithelial trepan for corneal cross-linking operations

A corneal cross-linking and epithelium technology, applied in the field of biomedical engineering, can solve the problems of uneven distribution of riboflavin, unstable duration, low absorption efficiency, etc., to avoid leakage and escape, reduce irritation, and stabilize control. Effect

Pending Publication Date: 2020-06-19
EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional method achieves the purpose of local infiltration of riboflavin in the cornea through frequency points or preparation of simple cotton ball rings, etc., but these methods have many limitations, mainly including uneven distribution of riboflavin, unstable duration, and Severe leakage and escape, etc., the absorption efficiency is low, which affects the surgical effect

Method used

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  • Epithelial trepan for corneal cross-linking operations
  • Epithelial trepan for corneal cross-linking operations

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Preparation of corneal epithelial trephine for cross-linking surgery, the ring wall is a single-leaf hyperboloid shape, the largest inner diameter of the ring is 8mm, the height of the epithelial trephine is 4mm, the upper and lower edges of the ring are blade-shaped, and the slope of the blade is 30 degrees . Suitable for patients with corneal diameter ≥ 12.5mm.

Embodiment 2

[0018] Prepare the corneal epithelial trephine for cross-linking surgery, the ring wall is a single-leaf hyperboloid shape, the maximum inner diameter of the ring is 10 mm, the height of the epithelial trephine is 5 mm, the upper and lower edges of the ring are blade-shaped, and the blade slope is 30 degrees . Suitable for patients with corneal diameter ≥ 12mm.

Embodiment 3

[0020] Prepare the corneal epithelial trephine for cross-linking surgery, the ring wall is a single leaf hyperboloid shape, the maximum inner diameter of the circle is 12 mm, the height of the epithelial trephine is 6 mm, the upper and lower edges of the ring are blade-shaped, and the blade slope is 30 degrees. Suitable for patients with corneal diameter <12.

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Abstract

The invention relates to an epithelial trepan for corneal cross-linking operations. The epithelial trepan is characterized in that the epithelial trepan is of a hollow structure with a ring wall in anunparted hyperboloid shape, and the outer sides of edge landing areas at the upper edge and the lower edge of the epithelial trepan form blade shapes. The epithelial trepan is suitable for corneal cross-linking operation, improves the action time stability and efficiency of riboflavin on corneal tissues during operation, and improves uniformity of absorption of liquid medicine by corneas. Consumption of a liquid medicine in the operation is reduced, the curative effect of the operation is improved, and the epithelial trepan is simple and safe to use. The epithelial trepan has the advantages of simple design and convenient manufacture.

Description

technical field [0001] The invention belongs to the field of biomedical engineering, and in particular relates to an epithelial trephine used for corneal cross-linking surgery. Background technique [0002] Corneal collagen cross-linking technology is a new treatment for keratoconus and corneal ectasia after laser keratorefractive surgery, which has emerged in recent years. The main principle is to use the photosensitizer riboflavin to form reactive oxygen species under the activation of ultraviolet light A wave (wavelength 370nm), and then induce the chemical cross-linking reaction between the amino groups of collagen fibers to increase the mechanical strength of the corneal stroma. [0003] Ensuring the level of riboflavin in the basal layer is one of the elements for successful cross-linking, which requires full contact and soaking of riboflavin with the cornea. The traditional method achieves the purpose of local infiltration of riboflavin in the cornea through frequenc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F9/007A61F9/00
CPCA61F9/007A61F9/0017
Inventor 徐海鹏杨卫明杨东李美燕周行涛
Owner EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
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