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Accurate and rapid microscopic image splicing method and system

A microscopic image, precise technology, applied in the direction of image enhancement, image analysis, image data processing, etc., can solve the problems of low stitching accuracy and low computational efficiency of microscopic image stitching, to reduce the amount of calculation, high similarity accuracy, The effect of improving work efficiency

Pending Publication Date: 2020-09-04
湖南国科智瞳科技有限公司
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  • Claims
  • Application Information

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Problems solved by technology

[0005] The present invention provides an accurate and fast microscopic image mosaic method and system, which are used to overcome the defects of low computational efficiency and low mosaic precision in microscopic image mosaic in the prior art

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  • Accurate and rapid microscopic image splicing method and system
  • Accurate and rapid microscopic image splicing method and system
  • Accurate and rapid microscopic image splicing method and system

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Embodiment Construction

[0025] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0026] In addition, the technical solutions of the various embodiments of the present invention can be combined with each other, but it must be based on the realization of those skilled in the art. When the combination of technical solutions is contradictory or cannot be realized, it should be considered as a combination of technical solutions. Does not exist, nor is it within the scope of protection required by the present invention.

[0027] The pre...

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Abstract

The invention discloses a microscopic image splicing method. The method comprises the steps: acquiring a local microscopic image sequence; carrying out cell detection on the local microscopic image toobtain a cell distribution situation, and estimating the area of a cell nucleus; according to the cell distribution condition, utilizing a brightness-based normalization cross-correlation characteristic algorithm to obtain the maximum value overlapping region and translation transformation of the adjacent local microscopic images; calculating the overlapping rate of the cell nucleus area in the maximum overlapping region according to the area of the cell nucleus, and comparing the overlapping rate with a preset overlapping rate threshold to obtain the confidence of translation transformation;according to the confidence coefficient, obtaining a splicing sequence of the local microscopic images by searching a minimum error path; and splicing the local microscopic images one by one according to the translation transformation and the splicing sequence. According to the method provided by the invention, automatic, rapid, accurate and seamless splicing of the microscopic images is realized, and seamless and accurate microscopic splicing can also be realized under the conditions of noise, blurring and extremely small overlapping area of the adjacent microscopic images.

Description

technical field [0001] The invention relates to the technical field of microscopic image processing, in particular to an accurate and fast microscopic image stitching method and system. Background technique [0002] Traditional microscopes have many problems in disease diagnosis and pathological research, such as many steps, heavy workload, difficult resource sharing, and inability to preserve them for a long time. To solve the above problems, the digital technology of pathological slides came into being. Considering the field of view limitation of high-magnification microscopes, the digitization of pathological slides uses microscopes to collect partial overlapping images of various parts of the slices, and combines multiple images into a large-scale panoramic microscopic image through image stitching technology. [0003] Generally speaking, the mosaic technology of microscopic images includes two steps: calculating the similarity of overlapping regions in the images collec...

Claims

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Application Information

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IPC IPC(8): G06T3/40G06T5/00G06T7/00G06T7/62G06K9/62
CPCG06T3/4038G06T7/0012G06T7/62G06T2207/10056G06T2207/30024G06T2207/30242G06F18/22G06T5/70
Inventor 谷秀娟向北海许会
Owner 湖南国科智瞳科技有限公司
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