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Perception training device and method for auditory cortex plasticity based on painless training stimulation and application

A technology of training device and training method, which is applied in the field of life science/medicine, achieves wide application prospects, improves auditory cortex dysfunction, and improves frequency selectivity

Active Publication Date: 2020-09-25
EAST CHINA NORMAL UNIVERSITY
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  • Abstract
  • Description
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AI Technical Summary

Problems solved by technology

For this reason, the current frequency perception training paradigm can only strengthen the task-related frequency representative area limitedly, which is manifested in the expansion of the area of ​​the task-related representative area and the strengthening of the function of the frequency representative area, while the frequency of neurons outside the task-related representative area Selectivity disappears or does not change

Method used

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  • Perception training device and method for auditory cortex plasticity based on painless training stimulation and application
  • Perception training device and method for auditory cortex plasticity based on painless training stimulation and application
  • Perception training device and method for auditory cortex plasticity based on painless training stimulation and application

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Experimental program
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Embodiment 1

[0050] The training process is generally divided into four stages. In the first stage, the rats gradually learn to trigger the photoelectric sensor (Nose-poke) during free activities in the experimental device, so as to obtain food rewards (Bio-Serve, 45mg). When the rat successfully triggers the sensor 100 times, it can enter the next stage. stage training. In the second stage, the horn gives a pure tone with a frequency of 6.5kHz (target frequency), and the rat needs to learn to touch the sensor after hearing the sound to obtain food rewards. Within 3 seconds after the target sound is given, if the rat triggers the sensor, it will be defined as Hit (Go), and a food reward will be obtained at the same time; otherwise, it will be defined as Miss (No-go), and it will be prompted to turn off the light for 12 seconds, waiting for recovery Lighting into the next training session. Every 100 training sessions is recorded as one round, and 10 rounds of training are performed every ...

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Abstract

The invention belongs to the technical field of life science / medicine, and discloses a perception training device for auditory cortex plasticity based on painless training stimulation. The training device is located in a sound insulation shielding box, and comprises a controller, a sound generator, a loudspeaker, a feeding device, an infrared nose detector and an illuminating lamp. The invention further discloses application of the training device in induction and perception training of the auditory cortex plasticity. The device has the characteristics of non-invasion, broad spectrum and the like, improves the frequency selectivity of auditory cortex neurons, and has a wide application prospect.

Description

technical field [0001] The invention belongs to the field of life science / medical technology, and relates to a technical solution for improving the plasticity of the brain sensory system and maintaining brain health, in particular to a sensory training device, method and application based on the plasticity of the auditory cortex without pain training stimulation. Background technique [0002] After birth in mammals, the brain undergoes a rapid maturation process. During the critical period of development, the structure and function of the brain are easily affected by factors such as environment and experience, and have great plasticity. However, for post-critical period (Post-critical period) adult animals, the induction, expression and regulation mechanism of brain plasticity are significantly different from those of juvenile animals in the critical period. For example, during the critical period, dynamic sound exposure can induce the structural reorganization (Reorganizat...

Claims

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Application Information

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IPC IPC(8): A01K15/02
CPCA01K15/029
Inventor 程远安鹏颖张贵敏周晓明
Owner EAST CHINA NORMAL UNIVERSITY
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