OCTA imaging method and device based on two-dimensional composite registration

Abstract

The invention discloses an OCTA imaging method and device based on two-dimensional composite registration. The invention discloses a two-dimensional composite registration method, a plurality of preliminary blood flow contrast images are used; after an OCTA effective strip is extracted, a global registration method based on large vessel skeleton registration degree and SIFT feature point extraction and a local registration method based on SIFT flow target function detection are used in a combined mode to perform registration on the OCTA effective strip pair on the two-dimensional level, and then motion artifacts are eliminated. The obtained fused OCTA result image is small in pixel average error, good in quality and high in structural similarity with an original OCTA blood flow contrast image, motion artifacts contained in the fused OCTA result image are greatly reduced and even disappear, and high-quality OCTA blood flow contrast imaging is achieved.

Description

technical field [0001] The present invention relates generally to the field of biomedical imaging, and more particularly to motion artifact correction and two-dimensional imaging associated with Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA). registration method. Background technique [0002] Since time-domain Optical Coherence Tomography (OCT) was first proposed in 1991, OCT technology as a non-invasive diagnostic tool has gradually been widely used in the field of biomedical imaging research. Soon after, researchers were keenly aware of the application prospects of OCT technology in the field of retinal detection. In order to obtain high-resolution retinal blood flow volume data and then image the retinal vascular network, Optical Coherence Tomography Angiography (OCTA) technology came into being. As an emerging in vivo tissue imaging technique, OCTA visualizes the retinal vascular network by detecting the reflectance of OCT signals...

AI Technical Summary

Problems solved by technology

Because this perfect preliminary angiogram cannot be obtained in practical applications, their registration method is limited by the quality of the template, and the requirements for the template are relatively high

In 2018, Ang Li et al. proposed a single OCTA image repair method based on microvessel detection and breach filling. This method avoids the complicated image acquisition process, but this method cannot repair the detail data that did not appear in the original image data. , local details are likely to be missing

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