DNA movable type storage system and method

Abstract

The invention discloses a DNA movable type storage system and method. The DNA movable type storage method comprises the following steps: providing a content movable type physical library and an indexmovable type physical library; splitting to-be-stored data in the target file into a plurality of data elements, marking index information for each data element, enabling the content information of the data elements to correspond to specific content movable type oligonucleotide fragments in a content movable type physical library, and enabling the index information to correspond to specific indexmovable type oligonucleotide fragments in an index movable type physical library; and then, connecting the content movable type oligonucleotide fragment and the index movable type oligonucleotide fragment to form a DNA movable type unit, and forming a DNA storage file in which all data elements to be stored are stored by a plurality of DNA movable type units. The DNA movable type physical librarycan be synthesized at a time, repeatedly used and freely combined, the DNA synthesis cost is greatly reduced, the labor and time investment for multiple times of design and synthesis of DNA fragmentscan be avoided, and the cost burden caused by introduction of a large number of error correction sequences is avoided.

Description

Technical field [0001] The present invention relates to the field of DNA storage, in particular to a storage system and method based on the idea of ​​DNA movable type. Background technique [0002] DNA storage technology is an emerging big data storage technology that breaks through the traditional storage methods that use solid media, such as hard disks, optical disks, and removable disks. Utilizing the natural information storage capacity of DNA bases, according to certain rules, traditional data such as text, pictures, sound, video files, etc., are converted from 0-1 binary codes to DNA (deoxyribonucleic acid) nucleotide quaternary codes (A, T, C, G combination), and then artificially synthesize a specific sequence of DNA to store data such as text, pictures, sounds, and video files, and then use the corresponding decoding means to completely read the restored data. In short, DNA storage technology is a technology that uses artificial synthesis of specific sequence DNA to sto...

AI Technical Summary

Problems solved by technology

In August 2012, the "Science" magazine published the landmark research results on DNA storage by George Church's research group. They applied DNA chips as data storage media for the first time and successfully converted various media files (including 53,400 words of HTML text files) , 11 JPG images, and 1 Javascript program) into a trillionth of a gram of DNA (1 shack); this study also reports a new one-to-one correspondence between bits (0-1 codes) and bases. The coding method makes DNA storage of large multimedia files possible, but the error rate of this coding method is still relatively high

[0006] Although DNA storage technology has many advantages that traditional data storage technology does not have, and related research has made great progress in recent years, it goes without saying that compared with traditional data storage technology, its disadvantages are also very obvious, mainly in two points : First of all, its price is very expensive, and storage and reading are time-consuming, which greatly limit its practical application

Specifically, the design ideas of the above-mentioned DNA storage technologies are more similar to the logical ideas of "engraving and printing", and their research and development mainly focus on the coding field of converting 0-1 computer binary language into DNA nucleotide quaternary language. The main disadvantages are The cost is high, each storage file needs to synthesize all the sequences encoding the DNA storage file, these sequence fragments cannot be reused, and the cost is high

Secondly, many current DNA storage technologies are prone to errors during DNA sequence synthesis and sequencing, so a large amount of redundant information is required for error correction, which increases the cost

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