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Data processing device and system for hypersplenic function diagnosis and application thereof

A data processing device and data technology, which can be applied to patient-specific data, instruments, informatics, etc., can solve the problems of long time, complicated operation, and adverse reactions in patients with denatured red blood cells by thermal denaturing red blood cell imaging methods.

Pending Publication Date: 2020-12-01
THE SECOND AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no simple and accurate objective diagnostic method at present. 99m Tc-sulfur colloid and 99m Tc-phytate was phagocytized by mononuclear macrophages in the spleen[Nazie Ilham, Liu Lishui, Wang Saigang, Baya. Clinical value of 99mTc-sodium phytate liver and spleen imaging in hypersplenism[J] .Xinjiang Medicine, 2016,46(12):1497-1498,1510.] Or use the spleen to store or phagocytize heat-denatured red blood cells and image [Du Yanrong, Chen Fang, Zhou Hui. Chemically prepared denatured 99mTc-RBC for spleen Preliminary study of functional imaging [J]. Chinese Journal of Nuclear Medicine, 1998, (4): 248.], but because more than 90% of technetium colloid imaging agents are intercepted by the liver, the radioactivity actually reaching the spleen is low; The imaging method takes a long time, the operation is complicated, there are many influencing factors, and there is a potential risk of adverse reactions in patients with denatured red blood cells. It is difficult to routinely carry out clinically. Therefore, the above methods are rarely used in clinical practice.
At present, there is no relevant report on its application in the detection of hypersplenism

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  • Data processing device and system for hypersplenic function diagnosis and application thereof
  • Data processing device and system for hypersplenic function diagnosis and application thereof
  • Data processing device and system for hypersplenic function diagnosis and application thereof

Examples

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Embodiment 1、99

[0084] Embodiment 1, 99m Tc-pyrophosphate (PYP) SPECT dynamic imaging in diagnosis of hypersplenism

[0085] This example aims to explore the use of 99m Feasibility and clinical value analysis of spleen time-radioactivity count curve in diagnosis of hypersplenism obtained by Tc-pyrophosphate (PYP) SPECT dynamic imaging.

[0086] 1. Materials and methods

[0087] 1. General information

[0088] Experimental group: 2 male patients, aged 52 and 42 years old respectively, with significantly decreased pancytopenia and splenomegaly, hypersplenism was considered clinically.

[0089] Patient 1, male, 51 years old. He was admitted to the hospital because of "maintenance hemodialysis for 20 years, dizziness and fatigue for more than 1 month, and fever for 10 days". The blood picture is low, and the blood routine is shown in Table 1 for details. CT showed splenomegaly (longest diameter 16.47cm × shortest diameter 10.53cm). 18 F-FDG PET / CT imaging showed splenomegaly, 18 F-FDG PET...

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Abstract

The invention discloses a data processing device and system for hypersplenic function diagnosis and application thereof. The invention provides a data processing device for hypersplenic function diagnosis, and the device comprises a data receiving module which receives the dynamic collection data of the radioactivity counting of the abdomen of a to-be-detected person; an image generation and processing module used for generating radioactivity development images of all time phases of the abdomen and drawing a spleen time-radioactivity curve; a data storage module used for storing a judgment threshold value; a data analysis module used for fitting the part, 10 minutes later, in the spleen time-radioactivity curve into a straight line to obtain an included angle value between the straight line and an x-axis positive semi-axis, and comparing the obtained clamping angle value with a judgment threshold value; and a judgment module used for judging that the to-be-detected person meeting the preset judgment condition is a patient suffering from the hypersplenic disease or a candidate is not a patient suffering from the hypersplenic disease or a candidate is not the patient suffering from the hypersplenic disease. The method for diagnosing the hyperthyroidism is the first method in China and abroad, and is very worthy of popularization.

Description

technical field [0001] The invention relates to a data processing device, a system and an application thereof for diagnosing hypersplenism. Background technique [0002] Hypersplenism (hypersplenism), referred to as hypersplenism, is a syndrome clinically manifested as splenomegaly, one or more types of blood cells decrease, and bone marrow hematopoietic cells proliferate accordingly. After splenectomy, the blood picture recovers and the symptoms are relieved. [0003] Blood cell reduction is very common in clinical work, and hypersplenism is one of the main reasons. Accurate etiological differential diagnosis determines the formulation of treatment plan, for example, assessment of spleen function determines whether a patient can benefit from splenectomy. However, there is no simple and accurate objective diagnostic method at present. 99m Tc-sulfur colloid and 99m Tc-phytate was phagocytized by mononuclear macrophages in the spleen[Nazie Ilham, Liu Lishui, Wang Saigang, B...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H10/20G16H10/60G16H30/20G16H30/40
CPCG16H10/20G16H10/60G16H30/20G16H30/40
Inventor 庞小溪李飞常文瑞陈红黄山申镐源
Owner THE SECOND AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIV