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Composition with tyrosinase inhibiting effect and application

A tyrosinase and composition technology, which is applied in the directions of drug combinations, active ingredients of hydroxyl compounds, medical preparations containing active ingredients, etc., can solve the problems of unsatisfactory curative effect, high cost, high cost and the like

Pending Publication Date: 2020-12-15
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many treatment techniques and anti-freckle products for chloasma, most of which are expensive and expensive; but the curative effect is not satisfactory, and almost all of them are accompanied by adverse reactions
Both resveratrol and oxidized resveratrol have antioxidant and tyrosinase inhibitory effects, but there is no research report on combining the two into a composition to inhibit tyrosinase

Method used

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  • Composition with tyrosinase inhibiting effect and application
  • Composition with tyrosinase inhibiting effect and application
  • Composition with tyrosinase inhibiting effect and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] A composition with the effect of inhibiting tyrosinase consists of resveratrol and oxidized resveratrol in a molar ratio of 0.11.

Embodiment 2

[0014] A composition capable of inhibiting tyrosinase consists of resveratrol and oxidized resveratrol in a molar ratio of 0.25.

Embodiment 3

[0016] A composition with the effect of inhibiting tyrosinase consists of resveratrol and oxidized resveratrol in a molar ratio of 0.43.

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PUM

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Abstract

The invention discloses a composition with a tyrosinase inhibiting effect and application. The composition is prepared from resveratrol and oxidized resveratrol according to the molar mass ratio of 0.11 to 9. Experiments prove that the composition has the effect of synergistically inhibiting tyrosinase, and can be used for treating chloasma, erythema after acne, freckles and age pigments, repairing after solarization and resisting oxidation.

Description

technical field [0001] The invention relates to a composition with antioxidant activity, in particular to a composition and application with the effect of inhibiting tyrosinase. Background technique [0002] Chloasma is the most common melanosis disease, mostly occurs in the exposed parts of the face of young and middle-aged women, affects the appearance, and is difficult to treat at the same time. It is a major disease problem that is difficult to solve in the medical field. Its characteristics are: the onset is affected by many factors (ultraviolet stimulation, inflammatory response, etc.), stubborn, and easy to relapse. There are many treatment techniques and freckle products for chloasma, most of which are expensive and expensive; but the curative effect is unsatisfactory, and almost all of them are accompanied by adverse reactions. Both resveratrol and oxidized resveratrol have antioxidant and tyrosinase-inhibiting effects, but there is no research report on combining ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/05A61P39/06A61K8/34A61Q19/02A61Q19/08A61Q19/00
CPCA61K8/347A61K31/05A61K2800/5922A61K2800/782A61Q19/004A61Q19/02A61Q19/08A61P39/06A61K2300/00
Inventor 靳佳慧王艳刘俊杰
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE