Topical and transdermal delivery of an iron chelator to prevent and treat chronic wounds

A technology of iron chelating agent and transdermal patch, which is applied in the direction of drug combination, skin disease, drug delivery, etc., and can solve problems such as not involved
CN112105345APending Publication Date: 2020-12-18陶托纳集团知识产权控股有限责任公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
陶托纳集团知识产权控股有限责任公司
Publication Date
2020-12-18

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Abstract

A transdermal patch for the treatment of Sickle Cell Ulcers is provided. The patch can facilitate the delivery of an iron chelator, such as DFO. The DFO can be encapsulated in a reverse micelle to enhance penetration into and absorption by the dermis. The patch can be used to accelerate healing and reduce pain associated with Sickle Cell Ulcers.
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Description

[0001] incorporated by reference

[0002] All publications and patent applications mentioned in this specification are herein incorporated by reference in their entirety to the same extent as if each individual publication or patent application was specifically and individually indicated to be incorporated by reference. Background technique

[0003] Chronic wounds that do not heal pose challenges for patients, healthcare professionals, and healthcare systems. It severely impairs the quality of life of millions of people and burdens society in lost productivity and healthcare costs.

[0004] Wound healing is a dynamic pathway that optimally leads to restoration of tissue integrity and function. Chronic trauma results when normal repair processes are interrupted. By understanding the biology of wound healing, physicians can optimize the tissue environment in which the wound resides. Wound healing is the result of cumulative processes including coagulation, inflammation, basal...

Claims

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