84results about How to "Prevention reduction" patented technology

A method of forming a silicided gate on a substrate having active regions, comprising the steps of: forming a first silicide in the active regions from a first material; and forming a second silicide in the gate from a second material, wherein the first silicide forms a barrier against the second material forming a silicide in the active regions during the second silicide forming step, wherein said second silicide is thicker than said first silicide.

The present invention provides a composition comprising a nicotine-containing material and an anti-cancer agent usable in the treatment and / or prevention or reduction of the risk of cancer and precancerous conditions as well as for preventing or reducing the risk of cancer recurrence. Furthermore, a composition comprising a nicotine-containing material and an anti-inflammatory agent usable in the treatment and / or prevention or reduction of the risk of inflammation, is provided. The nicotine containing composition can also include both an anti-cancer agent and an anti-inflammatory agent A device for administering the composition of the present invention to subjects can be a cigarette, smoking pipe, smokeless tobacco, electronic cigarette, transdermal patch or the like.

The present invention provides materials and methods relating to mildly polar fluid extracts of plant materials, such as Artemisia plant species, useful in methods for treating diabetes and methods for modulating the activity of glucagon-like peptide-1 (GLP-1), and in methods for modulating phosphoenol pyruvate carboxykinase (PEPCK) activity in a diabetes-specific manner. The extracts are generally non-toxic and non-mutagenic and may be administered to diabetics with beneficial effect on blood glucose levels. The extracts may also be administered to non-diabetics without deleterious effect. The plants are easily grown with a minimum of time, labor, and cost. Extracts are inexpensively and quickly prepared without the need for fractionation to remove potentially deleterious compounds, and the extracts may be administered to mammals such as humans through various routes, in a variety of forms, and at convenient concentrations.

A method of forming a silicided gate on a substrate having active regions, comprising the steps of: forming a first silicide in the active regions from a first material; and forming a second silicide in the gate from a second material, wherein the first silicide forms a barrier against the second material forming a silicide in the active regions during the second silicide forming step, wherein said second silicide is thicker than said first silicide.

Compositions particularly suitable for preventing or treating urinary tract infections in mammals, especially in humans, comprising a combination of components, the composition comprising an effective amount of: (A) cranberry concentrate, cranberry extract or both; (B) D-mannose; and at least one component selected from the group consisting of: (C) ascorbic acid; (D) bromelain; and (E) inulin. The compositions are preferably in the form of a liquid concentrate such as a beverage drink.

The present invention provides for the use of iota- and / or kappa-carrageenan for the manufacture of an antiviral pharmaceutical composition for the prophylaxis or treatment of a pathological condition or disease caused by or associated with an infection by a respiratory virus selected from the group consisting of orthomyxovirus, paramyxovirus, adenovirus and coronavirus. The present invention further provides for the use of fucoidan, in particular of high molecular weight fucoidan, for the manufacture of an antiviral pharmaceutical composition for the prophylaxis or treatment of a pathological condition or disease caused by or associated with an infection by a respiratory virus selected from the group consisting of orthomyxovirus and paramyxovirus.

The present invention provides a new forms of (R)—N-methylnaltrexone, and compositions thereof, useful as a peripheral mu opioid receptor antagonist.

The present invention concerns a detergent and a pharmaceutical composition comprising a deoxyribonuclease (DNase), wherein the DNase is obtained from a fungal source. It further concerns a laundering method and the use of DNase. The present invention further relates to polypeptides having DNase activity, as well as methods of producing the polypeptides.

A compound for the manufacturing of a medicament for reducing or preventing mesothelial cell damage includes a mixture of a carrier gas and between 1 volume percent and 29 volume percent of nitrous oxide gas (N2O) and can be used for prevention of adhesion formation, pain reduction, reducing or preventing acute inflammation, reducing or preventing CO2 resorbtion or reducing tumor cell implantation upon surgery.

The present invention concerns a method for increasing the solubility of an enzyme in a liquid detergent composition comprising one or more enzymes, an anionic surfactant and a solvent system, which liquid detergent composition has a Hansen Solubility Parameter hydrogen bonding contribution (δh) in the range of 2-35. In addition, the invention concerns a liquid detergent composition and use of the detergent composition.

The present invention relates to a system and method of transmitting an emergency condition using a wireless sensor network that transmits a user's emergency condition using a wireless sensor network. A wireless sensor network communication device integrated with a biological sensor is attached to a user's body in order to gather user's biological information, and transmits the user's biological information through the wireless sensor network. A repeater receives the biological information from the communication device, and sends the received biological information by using a routing protocol of the wireless sensor network. A management server receives the biological information through the repeater, analyzes the biological information, and transmits a warning signal to a user or takes emergency measures. Therefore, it is possible to detect and cope with sudden physical problems, which are generated during user's exercises and outdoor activities, at an early stage. As a result, it is possible to significantly contribute to the prevention and reduction of danger for the weak and the elderly, and a user who is to be taken care of.

The present invention relates to nanoparticles comprising a platelet-derived growth factor (PDGF) receptor tyrosine kinase inhibitor, especially a PDGF receptor tyrosine kinase inhibitor having a water-solubility at 20° C. between about 2.5 g / 100 ml and 250 g / 100 ml, more specifically nanoparticles comprising an N-phenyl-2-pyrimidine-amine derivative of formula I,in which the symbols and substituents have the meanings as given herein above, in free form or in pharmaceutically acceptable salt form; to the intracellular delivery of PDGF receptor tyrosine kinase inhibitors such as Imatinib with bio-absorbable polymeric nanoparticles; the use of such nanoparticles in the manufacture of a pharmaceutical composition for the treatment of vascular smooth muscle cells growth diseases; to a method of treatment of warm-blooded animals suffering from vascular smooth muscle cells growth diseases; to a process to prepare such nanoparticles; to pharmaceutical compositions comprising such nanoparticles; and to drug delivery systems incorporating such nanoparticles for the prevention and treatment of vascular smooth muscle cells growth diseases.

An electronic subassembly comprises a printed circuit board and an electronic module, particularly a ceramic module, electrically connected to one another through a planar interposer. The interposer comprises an insulator sheet and electrical spring elements joining contact sites on the module with contact pads on the PCB. The invention includes modifications that improve the integrity of electrical connections between the printed circuit board and the electronic module. This is achieved by compensating for non-planarity between the surfaces of the interposer and the module, particularly resulting from a convex curvature of the module, by minimizing relative movement, such as rocking in the x-z and y-z planes. It also includes modifications to the suspension of the module within the interposer housing to reduce the effects caused by any sliding that may occur between the interposer and the module in the x-y plane.

Non-cariogenic sugar-free confectionery compositions which deliver anti-plaque components to the mouth for oral health benefits and also deliver nutrients for systemic health benefits; wherein such confectionery compositions comprise of: (i) a safe and effective amount of natural tree, plants and tea extracts selected from moringa, matcha green tea, green tea, chia and mixtures thereof; (ii) one or more anti-plaque component or components; (iii) one or more natural, non-cariogenic, tooth-friendly sweetener or mixtures of sweeteners; (iv) a suitable confectionery carrier and (v) less than 10% water.

A freewheel coupling (1) is provided having clamping bodies (4), which are arranged between an inner ring (2) and an outer ring (3) and which have a narrow section (5). A single cage (9) is arranged between the inner ring (2) and the outer ring (3) with a plurality of pockets (10). Each of the pockets (10) has an area (12) that is narrower in the axial direction and an area (11), which is adjacent to this narrower area, which is wider in the axial direction, and which is provided for holding a clamping body (4). A spring band (6), which is arranged radially within the cage (9), has an original curvature in the unloaded state, wherein the curvature radius exceeds a radius of the cage (9), and spring tongues (13), which are provided for spring mounting of the clamping bodies (4), are directed radially inwardly.

The invention relates to novel compounds that are useful for modulating cellular ROS. The compounds are amide-derivatives of 2-hydroxy-2-methyl-4-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-butanoic acid. The compounds of the invention are formulated into pharmaceutical or cosmetic compositions. The invention further relates to methods wherein the compounds of the invention are used for treating or preventing diseases associated with increased ROS levels mitochondrial disorders and / or conditions associated with mitochondrial dysfunction, including adverse drug effects. The invention also relates to cosmetic methods for treating or delaying further aging of the skin and veterinary applications.

The present invention relates to compositions, methods and use of a mixture of enzymes having DNase activity and an enzyme having hexosaminidase activity.

The present invention concerns a detergent comprising a deoxyribonuclease (DNase). The present invention further relates to methods and uses of the detergent comprising a deoxyribonuclease (DNase) for laundering.

The use of glutathione to treat or prophylax viral, bacterial, chemical, and nuclear agents, or to treat or prophylax radiation injury to humans due to release of radioactive elements. The preferred formulation is an oral dosage form, with reduced glutathione stabilized by ascorbic acid, packaged to under controlled humidity and temperature conditions to ensure creation of charge transfer complexes that ensure consistent packaging, insignificant oxidation during packaging and subsequent normal storage, and high oral bioavailability for humans.

An object is to prevent abrasion inside an addition valve and clogging of the addition valve due to an increase in the particle diameter of precipitates. A first control is performed by which a pump is caused to operate in such a way as to return urea solution contained in the addition valve and a urea solution channel to a tank by a predetermined quantity. After the lapse of a certain time after the end of the first control, a second control is performed by which the pump is caused to operate in such a way as to return the urea solution remaining in the addition valve and the urea solution channel thoroughly to the tank.

An electronic subassembly comprises a printed circuit board and an electronic module, particularly a ceramic module, electrically connected to one another through a planar interposer. The interposer comprises an insulator sheet and electrical spring elements joining contact sites on the module with contact pads on the PCB. The invention includes modifications that improve the integrity of electrical connections between the printed circuit board and the electronic module. This is achieved by compensating for non-planarity between the surfaces of the interposer and the module, particularly resulting from a convex curvature of the module, by minimizing relative movement, such as rocking in the x-z and y-z planes. It also includes modifications to the suspension of the module within the interposer housing to reduce the effects caused by any sliding that may occur between the interposer and the module in the x-y plane.

A heater part of a planar sensor element includes: a Pt heater element; and an insulating layer including 90-99.9 wt % of an insulating material having a different coefficient of thermal expansion from a solid electrolyte forming a base part of the element. The heater part other than a heater electrode is buried in the base part. The heater element has a thickness of 10-50 μm and is covered with the insulating layer. The insulating layer has a porosity of 4% or less and a thickness of 50-150 μm. The distances of the insulating layer from an end portion of the element, from a main surface on which the heater electrode is located, and from a side surface of the element are respectively 0.25-0.75 mm, 0.20-0.60 mm, and 0.20-0.60 mm. The total length of the element is 80.0 mm or less.

The invention pertains to conjugates of the capsular polysaccharide of Vibrio cholerae O139, or a structurally and / or immunologically related oligo- or poly-saccharide, and a carrier. These conjugates are useful as pharmaceutical compositions and / or vaccines to induce serum antibodies which have bactericidal (vibriocidal) activity against V. cholerae, in particular V. cholerae O139, and are useful to prevent, treat and / or reduce the severity of disease caused by V. cholerae infection, such as cholera. The present invention also relates to diagnostic tests for V. cholerae infection, and / or cholera caused by V. cholerae infection, using one or more of the oligo- or poly-saccharide-carrier conjugates or antibodies described above.

The present invention relates to the use of a polypeptide having DNase activity for preventing biofilm on a textile, wherein said textile is unused or unworn. In another aspect, the present invention relates to a composition for preventing, reducing or removing biofilm and / or malodour, comprising a polypeptide having DNase activity and a malodour control component. In another aspect, the present invention relates to a method for preventing biofilm and / or the malodour formation on a textile.