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Lactobacillus paracasei TCI708 and use of Lactobacillus paracasei TCI708 for preparation of composition for removing glycation end products

A Lactobacillus, Paracheese technology, applied in the directions of Lactobacillus, drug combination, microorganism-based methods, etc., can solve the problems of DNA damage, DNA translocation, affecting the normal function of DNA, etc.

Active Publication Date: 2021-01-19
TCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In addition, the end products of glycation can also cause DNA translocation, causing DNA damage, thus affecting the normal function of DNA

Method used

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  • Lactobacillus paracasei TCI708 and use of Lactobacillus paracasei TCI708 for preparation of composition for removing glycation end products
  • Lactobacillus paracasei TCI708 and use of Lactobacillus paracasei TCI708 for preparation of composition for removing glycation end products
  • Lactobacillus paracasei TCI708 and use of Lactobacillus paracasei TCI708 for preparation of composition for removing glycation end products

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Embodiment Construction

[0024] The present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments, but not as a limitation of the present invention.

[0025] Lactobacillus paracasei TCI708 (Lactobacillus paracasei TCI708) is a bacterial strain of the genus Lactobacillus isolated from Yushan soil (alpine soil) in Taiwan, China. Lactobacillus paracasei TCI708 was deposited in the DSMZ German Microorganism Collection with the accession number DSM33482. Moreover, the Lactobacillus paracasei TCI708 has the function of removing advanced glycation end products (Advanced Glycation End Products, AGEs).

[0026] Lactobacillus paracasei TCI708 is a Gram-positive bacillus that can grow in an anaerobic environment and is a facultative anaerobic lactic acid bacterium. The growth temperature of Lactobacillus paracasei TCI708 is 35°C to 37°C. Moreover, it can survive in an environment with a pH value of 3 to 7.

[0027] In some embodiments, Lactobacillus...

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Abstract

The invention provides lactobacillus paracasei TCI708, and lactobacillus paracasei TCI708 is preserved in German Collection of Microorganisms and Cell Cultures (DSMZ) (the preservation number is DSM33482). The invention further provides use of lactobacillus paracasei TCI708 (Lactobacillus paracasei TCI708) in preparation of a composition for removing a glycation end product, wherein lactobacillusparacasei TCI708 is preserved in German Collection of Microorganisms and Cell Cultures (the preservation number is DSM33482).

Description

technical field [0001] The invention relates to a kind of Lactobacillus paracasei, in particular to a kind of Lactobacillus paracasei TCI708 (Lactobacillus paracaseiTCI708) and its use for preparing a composition for removing end-saccharification products. Background technique [0002] Glycation end products (Advanced glycation end products, AGEs) are non-reducible substances produced by the mutual polymerization of sugars and proteins and an irreversible reaction. [0003] Studies have found that glycation end products can change and affect the normal function of proteins. For example, glycation end products will link with other proteins to form macromolecules, thereby reducing the chance of protein being metabolized. In addition, the end products of glycation can also cause DNA translocation, causing DNA damage, thereby affecting the normal function of DNA. [0004] Glycation end products are not only produced in the human body, but also abundant in the daily diet. In a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20A23L33/135A61K35/747A61P17/00C12R1/225
CPCA23L33/135A61K35/747A61P17/00A23V2002/00C12R2001/225C12N1/205A23V2400/165A23V2200/318A61K8/99A61Q19/08A61Q19/00A61K2800/78A61Q19/007
Inventor 黄琡涵林咏翔
Owner TCI CO LTD