Preparation process of anesthetic drug composition
A preparation process and composition technology, applied in the field of preparation technology of anesthetic drug compositions, can solve the problems of poor patient tolerance, single component, patient injury, etc., and achieve the effects of good anesthesia effect and good drug effect.
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Embodiment 1
[0027] A preparation process of an anesthetic composition, the preparation process comprising the following steps;
[0028] S1: Lidocaine hydrochloride, menthol, glycerin, ethanol and polysorbate are weighed according to the prescription amount, and the ratio of lidocaine hydrochloride: menthol: glycerin: ethanol: polysorbate is 30 parts: 5 parts: 200 Parts: 1000 parts: 15 parts;
[0029] S2: first put ethanol and clear water into the mixing equipment to make a 5% ethanol solution, then add lidocaine hydrochloride and menthol to the mixing equipment, stir until dissolved, add glycerin and polysorbate after dissolving, Stir for 45 minutes;
[0030] S3: adjusting the pH value of the solution in the mixing device to 3, filtering the medicinal solution, and performing water replenishment and sterilizing filtration on the medicinal solution, and then potting the medicinal solution.
[0031] Select 2 adult mice with the same health status, inject one of the mice with the existing ...
Embodiment 2
[0033] A preparation process of an anesthetic composition, the preparation process comprising the following steps;
[0034] S1: Lidocaine hydrochloride, menthol, glycerin, ethanol and polysorbate are weighed according to the prescription amount, and the ratio of lidocaine hydrochloride: menthol: glycerol: ethanol: polysorbate is 100 parts: 25 parts: 1200 Parts: 4500 parts: 200 parts;
[0035]S2: first put ethanol and clear water into the mixing equipment to make an ethanol solution with a concentration of 90%, then add lidocaine hydrochloride and menthol to the mixing equipment, stir until dissolved, add glycerin and polysorbate after dissolving, Stir for 45 minutes;
[0036] S3: adjusting the pH value of the solution in the mixing equipment to 8.0, and then filtering the medicinal solution, and performing hydration and sterilizing filtration on the medicinal solution, and then potting the medicinal solution.
[0037] Select 2 adult mice with the same health status, inject o...
Embodiment 3
[0039] A preparation process of an anesthetic composition, the preparation process comprising the following steps;
[0040] S1: Lidocaine hydrochloride, menthol, glycerin, ethanol and polysorbate are weighed according to the prescription amount, and the ratio of lidocaine hydrochloride: menthol: glycerin: ethanol: polysorbate is 60 parts: 15 parts: 700 Parts: 2200 parts: 115 parts;
[0041] S2: first put ethanol and clear water into the mixing equipment to make a 50% concentration of ethanol solution, then add lidocaine hydrochloride and menthol to the mixing equipment, stir until dissolved, add glycerin and polysorbate after dissolving, Stir for 45 minutes;
[0042] S3: adjusting the pH value of the solution in the mixing device to 5, then filtering the medicinal solution, and performing hydration and sterilizing filtration on the medicinal solution, and then potting the medicinal solution.
[0043] Select 2 adult mice with the same health status, inject one of the mice wit...
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