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Vacuum-driven micro-fluidic chip sample injection device

A technology of microfluidic chip and sample injection device, which is applied in laboratory utensils, laboratory containers, chemical instruments and methods, etc., can solve the problems of complex preparation of microfluidic chips, and achieves simple structure, simple and fast operation. Effect

Active Publication Date: 2021-03-26
SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation of the microfluidic chip required by the sampling device is relatively complicated, requiring a sealed suction needle and an integrated negative pressure generating device

Method used

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  • Vacuum-driven micro-fluidic chip sample injection device
  • Vacuum-driven micro-fluidic chip sample injection device
  • Vacuum-driven micro-fluidic chip sample injection device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] This embodiment provides a vacuum-driven microfluidic chip sampling device. The sampling device includes a bracket and a base. The bracket and the base are connected by at least one elastic component. part, the bracket is located above the accommodating part, the bracket is provided with at least one through hole passing through the top and the bottom of the bracket, the through hole is provided with a pipeline with both ends being pointed, and the pipeline The length is greater than the length of the through hole, and the top of the bracket is provided with a limiting part corresponding to the through hole, and the limiting part is used to fix the container containing the sample for injection.

Embodiment 2

[0041] This embodiment provides a vacuum-driven microfluidic chip sampling device. The sampling device includes a bracket and a base. The bracket and the base are connected by at least one elastic component. part, the bracket is located above the accommodating part, the bracket is provided with at least one through hole passing through the top and the bottom of the bracket, the through hole is provided with a pipeline with both ends being pointed, and the pipeline The length is greater than the length of the through hole, and the top of the bracket is provided with a limiting part corresponding to the through hole, and the limiting part is used to fix the container containing the sample for injection. The accommodating part is a groove provided on the base;

[0042] The top of the base is provided with a positioning hole, the positioning hole accommodates the elastic assembly, the elastic assembly includes a fixed part and an elastic part located at one end of the fixed part, ...

Embodiment 3

[0045] This embodiment provides a vacuum-driven microfluidic chip sampling device, the structure of which is as follows: Figure 1a As shown, the sample injection device includes a bracket 2 and a base 1, the bracket 2 and the base 1 are connected by four elastic components, the base is provided with a groove for accommodating a microfluidic chip, and the bracket 2 is located on the Above the groove, the bracket 2 is provided with a through hole that runs through the top and bottom of the bracket 2, and a bidirectional needle 5 is fixed inside the through hole, and the length of the bidirectional needle 5 is greater than the length of the through hole. The top of the bracket is provided with a limit portion corresponding to the through hole, and the limit portion is used to fix the container containing the sample; the top of the base is provided with four positioning holes 3, and the positioning holes 3 accommodate the An elastic assembly; the elastic assembly includes a fixed ...

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Abstract

The invention provides a vacuum-driven micro-fluidic chip sample injection device, which comprises a support and a base, the support is connected with the base through at least one elastic assembly, the base is provided with an accommodating part for accommodating a micro-fluidic chip, the support is located above the accommodating part, the support is provided with at least one through hole penetrating through the top and the bottom of the support, a pipeline with two sharp ends is arranged in the through hole, the length of the pipeline is larger than that of the through hole, the top of thesupport is provided with a limiting part corresponding to the through hole, and the limiting part is used for fixing a container holding a sample introduction sample. The sample injection device is simple in structure, simple, convenient and rapid to operate and free of leakage in the sample injection process. The device can be suitable for sample containers and micro-fluidic chips of different structures, and accessories do not need to be additionally arranged on the chip.

Description

technical field [0001] The invention belongs to the technical field of microfluidic chips, and relates to a microfluidic chip sampling device, in particular to a vacuum-driven microfluidic chip sampling device. Background technique [0002] Microfluidic chips have been widely used in many research fields. Although syringe pumps and peristaltic pumps can achieve precise and reliable fluid control, these external power sources that cannot be integrated into microfluidic chips cannot meet the portability requirements for instant testing. sexual needs. Recently, many research groups have developed passive microfluidic chips using osmosis, capillary action, surface tension, pressure, gravity-driven flow, hydrostatic flow, and vacuum to achieve fluid flow. Among them, vacuum-driven microfluidic chips have been applied in many biological researches. Hosokawa et al. first reported the use of degassed PDMS to inject reagents into microchannels for sandwich immunoassays. The chip wa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/5027
Inventor 蒋兴宇耿春阳
Owner SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA