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Scutellaria baicalensis test method based on hypertensive mice and liquid medicine storage device and method

A test method, high blood pressure technology, applied in the field of scutellaria baicalensis test based on hypertensive mice, and the storage device and method of medicinal liquid, which can solve the problems of limited scutellaria baicalensis anti-tumor effect and anti-viral effect

Active Publication Date: 2021-04-09
李亚芹
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, such studies are mostly limited to the antitumor effect, antiviral effect, hepatoprotective effect and in vitro antioxidant effect of Scutellaria baicalensis.

Method used

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  • Scutellaria baicalensis test method based on hypertensive mice and liquid medicine storage device and method
  • Scutellaria baicalensis test method based on hypertensive mice and liquid medicine storage device and method
  • Scutellaria baicalensis test method based on hypertensive mice and liquid medicine storage device and method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0079] Embodiment 1: Scutellaria baicalensis test method based on hypertensive white mice, wherein, the experimental animals are:

[0080] 50 14-week-old spontaneously hypertensive rats, 10 common Wister rats, weighing 257±10 grams, clean grade, place of origin: an experimental animal center. Certificate No. 805108.

[0081] Experimental drugs and main reagent Scutellaria baicalensis. Benazepril. Reagent test kit.

[0082] laboratory apparatus:

[0083] Water bath constant temperature oscillator, vortex mixer IKA-MSZ type, low-speed desktop centrifuge, super thermostat, Stat-Fax-2100 microplate reader, high-speed refrigerated centrifuge, electronic analytical balance, animal dissection equipment and experimental bench.

[0084] Experimental process: Spontaneously hypertensive rats were randomly divided into the following groups: benazepril group, scutellaria baicalensis group (high, medium and low doses) and model group, with 10 rats in each group. There were 10 blank con...

Embodiment 2

[0099] Example 2, such as figure 2-- As shown in 5, the liquid medicine storage device of this embodiment is used for encapsulating the liquid medicine in the liquid medicine carrier 1; it includes a station transfer device 2; The transmission line 15; the transmission mold 16 is a hollow structure, and its upper port has a mold process notch 17;

[0100] Distributed on the transmission line 15 are:

[0101] The drop station 3 has a drop device 10 to place the liquid medicine carrier 1 on the transfer mold 16;

[0102] The adjustment station 4 has a pressing manipulator; the pressing manipulator is used to place the liquid medicine carrier 1 with an edge and an open upper end in the transfer mold 16;

[0103] The cleaning station 5 has an ozone blowing pipe 11, which is used to inject ozone gas into the liquid medicine carrier 1 for disinfection;

[0104] The filling station 6 has a filling machine 12 for filling the liquid medicine into the liquid medicine carrier 1;

[...

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Abstract

The invention relates to a scutellaria baicalensis test method based on hypertensive mice. The method comprises the following step of: preparing 10 clean-grade experimental animals, namely spontaneous hypertensive rats and Wister rats, experimental medicines, namely scutellaria baicalensis and benazepril, a kit, an experimental instrument, a water bath constant-temperature oscillator, a vortex mixer, a centrifugal machine, a thermostat, an enzyme-labeling instrument, an electronic analytical balance, an animal dissecting instrument and an experimental table. The invention further relates to a liquid medicine storage device and method. The liquid medicine storage device comprises a station conveying device (2) and is used for packaging liquid medicine in a liquid medicine carrier (1), wherein the station conveying device (2) comprises a conveying line (15) on which conveying molds (16) are distributed; the conveying molds (16) are of hollow structures, and mold process notches (17) are formed in the upper ports of the conveying molds (16). The device is reasonable in design, compact in structure and convenient to use.

Description

technical field [0001] The invention relates to a test method of Scutellaria baicalensis based on hypertensive white mice, a medicinal liquid storage device and a method. Background technique [0002] Scutellaria baicalensis belongs to labiatae, which was first recorded in "Shen Nong's Materia Medica", and has the functions of clearing away heat, purging fire, detoxifying, hemostasis, and preventing miscarriage. The chemical components of Scutellaria baicalensis mainly contain flavonoids, in addition, it also contains sitosterol, carotin and trace elements. At present, such studies are mostly limited to the antitumor effect, antiviral effect, hepatoprotective effect and in vitro antioxidant effect of Scutellaria baicalensis. WangQ et al. found that the effective components of Scutellaria baicalensis inhibited myocardial fibrosis and collagen hyperplasia, and concluded that the effective components of Scutellaria baicalensis had certain in vitro anti-oxidation, anti-myocardi...

Claims

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Application Information

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IPC IPC(8): A61K49/00A61K36/539A61P9/12A61P9/00B65B7/16B65B61/26
CPCA61K49/0008A61K36/539A61P9/12A61P9/00B65B7/164B65B61/26Y02A50/30
Inventor 李亚芹解诗语王乾一康世鑫崔红根
Owner 李亚芹
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