Method for researching alcoholic bone remodeling based on marrow fluid metabonomics

A metabolomics and alcohol-based technology, applied in the field of alcoholic bone remodeling based on bone marrow fluid metabolomics, can solve the problems of low reliability, unfavorable bone self-repair, and long cycle, so as to shorten the cycle and realize self-repair , the effect of improving reliability

Pending Publication Date: 2021-04-23
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Bone remodeling refers to the physiological behavior in which the shape and density of bone tissue change with changes in the biomechanical environment. Qualitatively speaking, in areas with higher loads, bone mass and density increase, while in areas with lower loads, bone mass and density increase. The quality and density of bone tissue decreases, and the characteristic of bone tissue that becomes stronger when used and becomes weaker when it is used reflects its adaptability to the biomechanical environment, so that it can achieve the maximum bearing capacity with the least amount of bone in a specific mechanical environment. ability, when the bone is in an unfavorable external force environmen

Method used

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Examples

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Effect test

Embodiment 1

[0024] The invention provides a technical solution:

[0025] A method for studying alcohol-induced bone remodeling based on bone marrow fluid metabolomics. The steps of bone remodeling include:

[0026] Step 1: Take a CT scan of the patient's leg with a malignant tumor to determine the extent of the tumor attached to the bone;

[0027] Step 2: Make the patient lie flat on the hospital bed, then cut open the tumor part of the patient's leg, and then cut off the bone with the tumor part through the cutting device;

[0028] Step 3: Use drilling equipment to drill positioning holes on the outside of the two severed bones, and then fix the two severed bones with two positioning devices;

[0029] Step 4: Put the severed bone with tumor in a glass bottle, then inject ethanol into the glass bottle, seal the glass bottle after the injection of ethanol is completed, so as to soak the bone with tumor in ethanol;

[0030] Step 5: Take out the soaked bones with tumors, and wipe off the e...

Embodiment 2

[0037] The invention provides a technical solution:

[0038] A method for studying alcohol-induced bone remodeling based on bone marrow fluid metabolomics. The steps of bone remodeling include:

[0039] Step 1: Take a CT scan of the patient's leg with a malignant tumor to determine the extent of the tumor attached to the bone;

[0040] Step 2: Make the patient lie flat on the hospital bed, then cut open the tumor part of the patient's leg, and then cut off the bone with the tumor part through the cutting device;

[0041] Step 3: Use drilling equipment to drill positioning holes on the outside of the two severed bones, and then fix the two severed bones with two positioning devices;

[0042] Step 4: Put the severed bone with tumor in a glass bottle, then inject ethanol into the glass bottle, seal the glass bottle after the injection of ethanol is completed, so as to soak the bone with tumor in ethanol;

[0043] Step 5: Take out the soaked bones with tumors, and wipe off the e...

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Abstract

The invention relates to the technical field of bone remodeling, in particular to a method for researching alcoholic bone remodeling based on marrow fluid metabonomics. The bone remodeling steps comprise: Step 1, performing CT (Computed Tomography) on a leg of a patient suffering from a malignant tumor so as to determine the range of the tumor attached to the bone; Step 2, enabling the patient to lie flat on a sickbed, then splitting the tumor part of the leg of the patient, and next cutting off the bone with the tumor part through cutting-off equipment; and Step 3, drilling positioning holes in outer sides of two sections of the cut bone through hole drilling equipment. By using the method, the cut-off bone is subjected to soaking tumor removing treatment, and is then reset again; through cooperation with autonomous metabolism of marrow fluid and auxiliary supporting extrusion of a positioning mechanism, the bone remodeling effect is guaranteed, and the bone remodeling period is also shortened; an additional supporting mechanism does not need to be additionally added to the remodeling part, so that a repulsion phenomenon is avoided; the self repair of bone remodeling is well realized; and the reliability of bone remodeling is greatly improved.

Description

technical field [0001] The invention relates to the technical field of bone remodeling, in particular to a method for studying alcoholic bone remodeling based on bone marrow fluid metabolomics. Background technique [0002] Bone remodeling refers to the physiological behavior in which the shape and density of bone tissue change with changes in the biomechanical environment. Qualitatively speaking, in areas with higher loads, bone mass and density increase, while in areas with lower loads, bone mass and density increase. The quality and density of bone tissue decreases, and the characteristic of bone tissue that becomes stronger when used and becomes weaker when it is used reflects its adaptability to the biomechanical environment, so that it can achieve the maximum bearing capacity with the least amount of bone in a specific mechanical environment. ability, when the bone is in an unfavorable external force environment, its shape and density will undergo abnormal changes, suc...

Claims

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Application Information

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IPC IPC(8): A61F2/46
CPCA61F2/4603A61F2/4644A61F2/4675A61F2002/286A61F2002/4646A61F2002/4648
Inventor 不公告发明人
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE
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