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Cream for treating infant eczema and preparation method thereof

A technology for infant eczema and cream, applied in the field of cream for treating infant eczema and its preparation, can solve the problems of easy recurrence, poor compliance of infants and young children, growth inhibition and the like

Inactive Publication Date: 2021-05-18
XINJIANG CICONHABO UYGUR MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Symptomatic treatment is often used in treatment, but it is easy to relapse and cannot be cured, and it is easy to relapse and has many side effects.
[0003] At present, there is no specific drug for the treatment of eczema in Western medicine. In clinical practice, compound preparations of corticosteroid hormones are often used to treat infantile eczema, but long-term use may cause dependence and adverse reactions.
Moreover, because the skin of infants and young children is thin and tender and the body surface area is relatively large, the drug transdermal absorption when they take medicine is higher than that when adults take medicine. Infants and young children are more likely to inhibit the hypothalamus-pituitary-adrenal axis through systemic absorption than adults. Even with weak corticosteroids, long-term use may also cause growth inhibition.
[0004] Due to the poor compliance of infants and young children, the adherence to oral medicines is low; in addition, hormone drugs are commonly used in clinical external medicines, and the parents of the children have low acceptance and rejection

Method used

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  • Cream for treating infant eczema and preparation method thereof
  • Cream for treating infant eczema and preparation method thereof
  • Cream for treating infant eczema and preparation method thereof

Examples

Experimental program
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preparation example Construction

[0042] The preparation method of above-mentioned emulsifiable paste, comprises the following steps:

[0043] (1) prepare comfrey oil:

[0044] After wetting the comfrey, put it in sesame oil, fry until the comfrey becomes dry, and the oil is purple black, remove the residue and filter to get the comfrey oil;

[0045] (2) Prepare the oil phase part: heat horse oil, comfrey oil, stearic acid, glyceryl monostearate, petrolatum, ethyl p-hydroxybenzoate, and laurocapram, and mix well to obtain the oil phase part;

[0046] Prepare the water phase: heat water, glycerin, and triethanolamine and mix them evenly to obtain the water phase;

[0047] (3) Preparation of cream: gradually add the water phase part into the oil phase part, and keep stirring until the water phase part is added, and after stirring into a cream shape, add gallic powder, stir until mixed evenly, cool To room temperature, get the described for the treatment of infantile eczema.

[0048] Preferably, in the step (...

Embodiment 1

[0056] Raw material preparation: 5 parts of comfrey, 5 parts of gall, 3 parts of horse oil, 5 parts of stearic acid, 4 parts of glyceryl monostearate, 1 part of laurozone, 2 parts of vaseline, 6 parts of glycerin, 1 part of triethanolamine 50 parts of water, 0.1 part of ethyl p-hydroxybenzoate.

[0057] Weigh raw materials according to raw material preparation, specific operation steps:

[0058] (1) prepare comfrey oil:

[0059] Xinjiang comfrey is moistened with a small amount of water, quickly placed in sesame oil at 120-140°C for frying, until the comfrey becomes dry and the oil is purple-black, the residue is removed and filtered to obtain comfrey oil.

[0060] Wherein, the mass ratio of sesame oil to Xinjiang comfrey is 5-7:1. The way of frying in a small amount and multiple times is conducive to improving the safety of operation.

[0061] (2) Grinding the galls into fine powder at low temperature to obtain gallons powder.

[0062] (3) Prepare the oil phase part:

[00...

Embodiment 2

[0069] Raw material preparation: 1 part of comfrey, 3 parts of gall, 3 parts of horse oil, 3 parts of stearic acid, 3 parts of glyceryl monostearate, 0.5 part of laurozone, 1 part of petrolatum, 5 parts of glycerin, 0.5 part of triethanolamine parts, 45 parts of water, 0.05 parts of ethyl p-hydroxybenzoate.

[0070] Weigh raw materials according to raw material preparation, specific operation steps:

[0071] (1) prepare comfrey oil:

[0072] Xinjiang comfrey is moistened with a small amount of water, quickly placed in sesame oil at 125°C for frying, until the comfrey becomes dry and the oil is purple-black, the residue is removed and filtered to obtain comfrey oil.

[0073] Wherein, the mass ratio of sesame oil to Xinjiang comfrey is 6:1. The way of frying in a small amount and multiple times is conducive to improving the safety of operation.

[0074] (2) Grinding the galls into fine powder at low temperature to obtain gallons powder.

[0075] (3) Prepare the oil phase par...

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Abstract

The invention relates to cream for treating infant eczema and a preparation method thereof. The cream for treating the infant eczema is prepared from the following raw materials of radix arnebiae, nutgall, horse oil, stearic acid, glyceryl monostearate and glyceryl distearate, azone, vaseline, glycerin, triethanolamine, water and ethyl p-hydroxybenzoate. The invention also discloses a preparation method of the cream. According to the cream for treating the infant eczema and the preparation method thereof, the medicines in a prescription are all natural Chinese herbal medicine plants, the prescription is rigorous and refined, and the cream is good in curative effect, quick to absorb, high in safety and small in side effect.

Description

technical field [0001] The invention specifically relates to a cream for treating infantile eczema and a preparation method thereof. Background technique [0002] Infant eczema is a clinically common acute, subacute, and chronic skin allergic and itchy inflammation. It belongs to the category of damp toxin and fetal toxin in traditional Chinese medicine. Symptoms of acute onset in children often include small vesicles, papules, and exudates in local skin lesions; symptoms of repeated infiltration, itching, hypertrophy, pigmentation, roughness, and scaly surfaces are common in chronic phase, which interfere with sleep in children and affect its health and growth. Western medicine believes that the occurrence of eczema is varied and complicated. At present, a large number of studies have confirmed that there are a variety of inflammatory cells infiltrated in eczema lesions, and a large number of inflammatory mediators are released, thereby promoting the occurrence of inflamm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/30A61K47/12A61K47/14A61K47/10A61K47/06A61K47/22A61K9/06A61P17/00A61K35/64A61K35/35
CPCA61K36/30A61K35/64A61K35/35A61K47/12A61K47/14A61K47/10A61K47/06A61K47/22A61K9/06A61P17/00
Inventor 季志红陈金成马璇李柯翱张明惠
Owner XINJIANG CICONHABO UYGUR MEDICINE
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