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Microstructure

A structural and miniature technology, applied in the direction of microneedles, devices introduced into the body, hypodermic injection devices, etc., can solve the problems of inability to achieve quantitative delivery, uneven drug amount, skin irritation, etc., to shorten the attachment time, reduce side effects, The effect of preventing sweating

Inactive Publication Date: 2021-05-25
IND ACADEMIC CORP FOUND YONSEI UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the existing micropatch requires different application times of the patch depending on the skin condition of the subject
In this case, as the attachment time of the micropatch increases, side effects such as skin irritation and inflammation are caused to the application target
[0005] Also, before the drug contained in the microstructure is absorbed into the skin due to sweating or an increase in body temperature, a part of the drug melts outside the skin and remains in the patch, so the amount of the drug delivered to the skin is uneven , unable to achieve the purpose of quantitative delivery

Method used

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Embodiment Construction

[0050] Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings, so that those skilled in the art to which the present invention pertains can easily realize the present invention. The present invention can be realized in various embodiments and is not limited to the examples described in this specification. In order to clarify the present invention, parts irrelevant to the description are omitted from the drawings, and the same reference numerals are assigned to the same or similar structural elements throughout the specification.

[0051] Next, a microstructure according to an embodiment of the present invention will be described in more detail with reference to the accompanying drawings. figure 1 is a cross-sectional view of a microstructure according to a first embodiment of the present invention, figure 2 is a cross-sectional view of a microstructure according to a second embodiment of the present invention...

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PUM

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Abstract

A microstructure is provided. A microstructure according to an embodiment of the present invention comprises: a tip portion formed on a substrate and comprising a drug; and a separation portion which is formed between the substrate and the tip portion and, after the tip portion has been inserted into the skin, separates the substrate and the tip portion physically by means of an external force or chemically by means of a chemical material.

Description

technical field [0001] The present invention relates to a microstructure, in particular, to a microstructure that can be used to deliver medicine into the skin. Background technique [0002] Oral administration of tablets or capsules or needle administration is generally used to deliver drugs for disease treatment or cosmetics into the body. Recently, various microstructures including microneedles have been developed. The microstructures developed so far are mainly used for drug delivery in vivo, blood collection, and detection of analytes in vivo. [0003] The biodegradable microstructure does not dissolve immediately after being inserted into the skin, and it takes several minutes to tens of minutes to completely dissolve depending on the substance used. Therefore, in order to prevent the microstructures from detaching from the skin while the microstructures are being inserted into the skin and dissolved in the skin, a patch capable of being fixed to the skin is used. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00A61K9/00
CPCA61K9/0021A61M37/0015A61M2037/0046A61M2037/0061A61M37/0069A61M2202/0484
Inventor 丁炯一梁辉锡姜虔禹
Owner IND ACADEMIC CORP FOUND YONSEI UNIV
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