Traditional Chinese medicine active ingredient formula for treating postmenopausal osteoporosis and application of traditional Chinese medicine active ingredient formula

A technology for osteoporosis and active ingredients, applied in the field of medicine, can solve the problems of inconvenience in carrying, taking, and unclear ingredients, and achieve the effects of abundant raw materials, high economic and social benefits, and convenient preparation methods

Active Publication Date: 2021-06-04
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Treatment should be based on tonifying the kidney, strengthening the bones, and activating blood circulation. Many traditional Chinese medicine prescriptions are used in the treatment, but there are deficiencies such as carrying, inconvenient taking, and unclear ingredients.

Method used

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  • Traditional Chinese medicine active ingredient formula for treating postmenopausal osteoporosis and application of traditional Chinese medicine active ingredient formula
  • Traditional Chinese medicine active ingredient formula for treating postmenopausal osteoporosis and application of traditional Chinese medicine active ingredient formula
  • Traditional Chinese medicine active ingredient formula for treating postmenopausal osteoporosis and application of traditional Chinese medicine active ingredient formula

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Effect test

Embodiment 1

[0039] In the specific implementation of the present invention, the active component prescription of the traditional Chinese medicine of the present invention consists of 50 mg of wolfberry polysaccharide, 6 mg of icariin, 50 mg of polydatin, 1 mg of quercetin, and 10 mg of danshensu sodium.

Embodiment 2

[0041] In the specific implementation of the present invention, the composition of active ingredients of the traditional Chinese medicine of the present invention consists of 350 mg of wolfberry polysaccharide, 50 mg of icariin, 180 mg of polydatin, 10 mg of quercetin, and 100 mg of danshensu sodium.

Embodiment 3

[0043]In the specific implementation of the present invention, the active component prescription of the traditional Chinese medicine of the present invention consists of 200 mg of wolfberry polysaccharide, 30 mg of icariin, 120 mg of polydatin, 5 mg of quercetin, and 60 mg of danshensu sodium.

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PUM

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Abstract

The invention provides a traditional Chinese medicine active ingredient formula for treating postmenopausal osteoporosis and application of the traditional Chinese medicine active ingredient formula, and belongs to the field of medicines. The traditional Chinese medicine active ingredient formula comprises traditional Chinese medicine active ingredients including lycium barbarum polysaccharide, icariin, polydatin, quercetin and salvianic acid A sodium which are calculated according to the weight (mg) ratio of (50-350): (6-100): (50-180): (1-10): (10-100). The traditional Chinese medicine active ingredient formula is reasonable in compatibility; the ingredients supplement each other; the traditional Chinese medicine active ingredient formula is definite in curative effect and high in innovativeness, and can be effectively applied to treatment of the postmenopausal osteoporosis; and repeated verification shows that the formula can remarkably increase the bone density of an animal with a postmenopausal osteoporosis model, improves the bone microstructure, is safe and effective, and can be used as a long-term medicine for the postmenopausal osteoporosis. The traditional Chinese medicine active ingredient formula can be further prepared into a medicinal preparation, is small in dosage form, is convenient to carry and take, has good economic and social benefits, and has a wide application prospect.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to a prescription of active ingredients of traditional Chinese medicine for treating postmenopausal osteoporosis and its application. Background technique [0002] Postmenopausal osteoporosis is a public health problem that seriously threatens the health of middle-aged and elderly people, with about 200 million patients worldwide. Among women over 60 years old in my country, the prevalence of osteoporosis is as high as 40% to 50%, and about 30% to 50% of them will experience osteoporosis-related fractures, which will seriously affect the health of the elderly and quality of life, leading to shortened lifespan. In my country, according to statistics, there are more than 90 million patients with osteoporosis and related fractures, and the annual medical expenses exceed 25 billion yuan, which seriously increases the financial and human burden of the country and families ("China White Paper on O...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61K31/7048A61K31/05A61K31/352A61K31/192A61P19/10A61P15/12
CPCA61K31/715A61K31/7048A61K31/05A61K31/352A61K31/192A61P19/10A61P15/12A61K2300/00
Inventor 朱晓峰张荣华杨丽孙珂焕梅雯惠辛灵崔琰
Owner JINAN UNIVERSITY
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