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Refrigeration device for stem cell culture

A stem cell culture and refrigeration device technology, applied in the field of cell culture equipment, can solve problems such as inconvenient access, inconvenient operation, and high heat dissipation requirements

Active Publication Date: 2021-06-08
济南创泽生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This patent application adopts the method of opening the box door to take the culture bottles placed on the tray, which has the problem of inconvenient access, and the device is not easy to cooperate with other operating procedures in cell culture, such as using a pipetting device to absorb liquid. It is inconvenient to operate and seriously affects the culture efficiency of stem cells
[0005] The Chinese utility model patent with the patent application number CN201920082669.8 discloses a cytology refrigerated storage box with automatic identification, including a box body and multiple splints in the box body, culture bottles are placed in the splints, and the lower part of the box cover The installation box is equipped with a semiconductor cooling chip, because the use of a semiconductor cooling chip requires high heat dissipation conditions, the patent only uses a semiconductor cooling chip for cooling, which can easily cause the cooling chip to burn out, seriously affecting the cooling effect, and the patent’s The box cover is connected to the box body through a lock, which is not easy to cooperate with other operating procedures in cell culture. For example, it is inconvenient to operate when using a pipetting device to absorb liquid, which seriously affects the culture efficiency of stem cells.

Method used

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  • Refrigeration device for stem cell culture
  • Refrigeration device for stem cell culture
  • Refrigeration device for stem cell culture

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Please refer to Figure 1-Figure 6 As shown, a cold storage device 50 for culturing stem cells includes:

[0052] The controller box 510 includes an upper box cover 511 and a lower box cover 512, and the controller box 510 is provided with a controller 513 connected to a power supply;

[0053] Refrigerator 520 is located on the top of controller box 510. Refrigerator 520 includes upper cover 521 and bottom plate 522, front side wall 523 and rear side wall 524, left side wall 525 and right side wall 526. Bladder 527, the upper opening of the inner tank 527, the lower end surface of the upper cover 521 is provided with a heat-insulating material protrusion 528 matching the upper opening contour of the inner tank 527, so that the heat-insulating material protrudes when the inner tank is in a refrigerated or heat-preserving state. The peripheral side edge of the inner container is in contact with the upper opening edge of the liner for sealing; the insulation material proj...

Embodiment 2

[0072] Please refer to Figure 7-Figure 8 As shown, the difference from Embodiment 1 is that the transmission assembly in this embodiment includes a bracket 590, a guide block 591 and a guide rail 592, and the guide block 591 cooperates with the guide rail 592 to realize that the guide rail 592 moves on the guide block 591, and the bracket 590 The upper end of the bracket 590 is connected with the lower end of the upper cover 521, the lower end of the bracket 590 is connected with the guide block 591, and the guide rail 592 is located on the inner side of the right side wall 526. In this embodiment, the cooperation mode between the guide block 591 and the guide rail 592 can be as follows: a groove matched with the guide rail 592 is provided on the guide block 591, the guide rail 592 passes through the groove and can move relative to the guide block 591, and the guide block 591 guides and limits the guide rail 592.

[0073] The upper cover 521 is driven to move relative to the...

Embodiment 3

[0075] Please refer to Figure 9-Figure 14 As shown, different from Embodiment 1 and Embodiment 2, in this embodiment, a motor 570, a connecting seat, a rotating shaft 572 and a sector gear 573 are arranged on the inner side of the front side wall 523, and the motor 570 is electrically connected to the controller 513. A notch 574 is provided at the position corresponding to the power output end of the motor at the upper end of the front side wall 523, and the connecting seat includes two L-shaped plates 571 respectively arranged on both sides of the notch, and each L-shaped plate 571 includes The long plate surfaces 5711 and short plate surfaces 5712 perpendicular to each other, the long plate surfaces 5711 of the two L-shaped plates are connected to the inner surface of the front side wall 523, the short plate surfaces 5712 of the two L-shaped plates are arranged opposite, and the two L-shaped plates The short plate surface 5712 of the shaped plate is respectively provided wi...

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Abstract

The invention discloses a refrigeration device for stem cell culture. The refrigeration device comprises a controller box and a refrigerating box, wherein the controller box is internally provided with a controller connected with a power supply; the refrigerating box is arranged on the upper portion of the controller box, an inner container is arranged in the refrigerating box, an opening is formed in the upper portion of the inner container, the lower end face of the upper cover is provided with a heat preservation substance protrusion matched with the outline of the opening in the upper portion of the inner container, and the refrigerating assembly comprises a water cooling circulation loop jointly formed by a semiconductor chilling plate, a water pipe, a water tank, a water pump, a radiator and a water cooling head. The upper box cover is provided with a penetrating opening, and an extending air cylinder is further arranged in the controller box. The upper cover is opened through a motor or a linear module. According to the device, the box cover of the refrigerating box can be automatically opened, the height of the refrigerating box can be adjusted, the temperature in the refrigerating box can be accurately adjusted by arranging the semiconductor chilling plate, the requirement for refined and automatic culture of stem cells is met, and the culture efficiency is higher.

Description

technical field [0001] The invention relates to the technical field of cell culture equipment, in particular to a refrigeration device for stem cell culture. Background technique [0002] Stem cell culture is one of the core links of biotechnology research, and it is widely used in vaccine production, biopharmaceuticals, and cell therapy. In the prior art, experimenters usually use stem cell culture devices for cell culture. [0003] The refrigerator is one of the components of the stem cell culture device. It has the function of refrigeration or heat preservation. It can be used to temporarily store the culture medium and use the controllable temperature to help the growth of stem cells. It is of great significance to satisfy the refined and automated culture of cells. [0004] For example, the Chinese invention patent application with the patent application number CN201811287285.6 discloses a cell culture refrigerator for biotechnology, which includes a refrigerator body a...

Claims

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Application Information

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IPC IPC(8): A01N1/02
CPCA01N1/0252
Inventor 王泽南陈晓光邢志青李士行
Owner 济南创泽生物医药科技有限公司