Separation and purification device for microglial cells

Abstract

The invention discloses a separation and purification device for microglial cells. The separation and purification device for the microglial cells comprises a main body frame, layer plates and a crushing box, wherein drawers are mounted on the front side surface of the main body frame; cabinet bodies are arranged below the drawers; bases are mounted at four corners of the bottoms of the cabinet bodies; an enclosure frame is mounted at the periphery of the outer edge of the upper part of the main body frame; a top frame is mounted at the upper part of the rear side of the enclosure frame; sliding rails are fixed to the inner walls of the left side and right side of the top frame; sliding blocks are connected to the inner sides of the sliding rails; each layer plate is mounted between the corresponding adjacent sliding blocks; rotating plates are arranged on the left side and right side of the upper part of each layer plate; rotating shafts are mounted at the joints of the rotating plates and the layer plates; the crushing box is mounted on the rear sides of the drawers; and crushing cutter bars are mounted inside the crushing box. According to the separation and purification device for the microglial cells, the crushing cutter bars are arranged and can crush experimental garbage inside the crushing box in the rotating process, and the crushed experimental garbage is more convenient to package, so that the treatment effect of the whole device on the experimental garbage is greatly enhanced.

Description

technical field [0001] The invention relates to the technical field of experimental equipment, in particular to a device for separating and purifying microglial cells. Background technique [0002] Microglia, a type of glial cell, are equivalent to macrophages in the brain and spinal cord, and are the first and most important line of immune defense in the central nervous system (CNS). Microglia make up about 20 percent of the glial cells in the brain. Microglia are constantly clearing damaged nerves, plaques, and infectious material from the central nervous system. Numerous clinical and neuropathological studies have shown that activated microglia play an important role in the pathogenesis of neurodegenerative diseases, such as Parkinson's disease, multiple sclerosis and Alzheimer's disease. But too many activated or out-of-control microglia can cause neurotoxicity. They are an important source of pro-inflammatory factors and oxidative stress, such as tumor necrosis facto...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a microglia separation and purification device, which solves the inconvenience of cleaning the separation and purification test benches in the market at the later stage during the use process, and it is not convenient to crush the experimental waste, and there are still separation and purification problems. The operating experimental equipment is inconvenient to install and fix, and it is also inconvenient to access

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