Moisture-proof five-ingredient detoxication drink granules and preparation method thereof

A technology of Wuwei Disinfection Decoction and granules, applied in antiviral agents, anti-inflammatory agents, pharmaceutical formulations, etc., can solve the problems of physical changes and chemical changes of drugs, affecting curative effect and other problems

Active Publication Date: 2021-09-17
JIANGZHONG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Based on this, the purpose of the present invention is to solve the problem that in the existing traditional Chinese medicine preparations, the universal moisture absorption causes physical changes and chemical changes in the medicine, thereby affecting the curative effect.

Method used

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  • Moisture-proof five-ingredient detoxication drink granules and preparation method thereof
  • Moisture-proof five-ingredient detoxication drink granules and preparation method thereof

Examples

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preparation example Construction

[0063] see figure 1 , The present invention proposes a preparation method of moisture-proof Wuwei Xiaoxiaoyin granules for preparing the above-mentioned moisture-proof Wuwei Xiaoxiaoyin granules, wherein the method comprises the following steps:

[0064] Step 1: Mix honeysuckle, wild chrysanthemum, dandelion, violet root and Tiankuizi, add water for decocting, then add rice wine to continue decocting, repeat twice, sieve the combined medicinal liquid and concentrate to obtain concentrated Liquid A.

[0065] Specifically, in this step, 2.5 parts of honeysuckle, 1 part of wild chrysanthemum, 1 part of dandelion, 1 part of Radix vulgaris, and 1 part of Tiankuizi are mixed to obtain a mixed medicinal material, and 5-20 times the volume of water of the mixed medicinal material is added, Boil for 50min. Continue to add rice wine with 5 times the volume of the mixed medicinal materials, and continue to cook for 10 minutes, for a total of 1 hour. Repeat the above steps twice, combi...

Embodiment 1

[0076] The first embodiment of the present invention provides a method for preparing moisture-proof Wuwei Xiaoxiaoyin granules, wherein the preparation method comprises the following steps:

[0077] Step 1: Mix 2.5 parts of honeysuckle, 1 part of wild chrysanthemum, 1 part of dandelion, 1 part of violet radix and 1 part of Tiankuizi to obtain mixed medicinal materials, add 5 times the volume of water of the mixed medicinal materials, and cook for 50min; continue to add and mix The rice wine with 5 times the volume of the medicinal materials was continuously decocted for 10 minutes, for a total of 1 hour. Then repeat the above steps twice, combine the medicinal solutions obtained twice, pass through a 200-mesh sieve, and concentrate to a density of 1.05 and a solid content of 15% to obtain concentrated solution A.

[0078] Step 2: Take 90 parts of concentrated solution A, add 10 parts of the first auxiliary material, pass through a colloid mill to mix evenly, pass through a 100...

Embodiment 2

[0089] The preparation method of the moisture-proof Wuwei Xiaoxuanyin granules proposed in the second embodiment of the present invention, wherein the preparation method comprises the following steps:

[0090] Step 1: Mix 2.5 parts of honeysuckle, 1 part of wild chrysanthemum, 1 part of dandelion, 1 part of Radix Radix et Rhizoma and 1 part of Tiankuizi to obtain mixed medicinal materials, add 10 times the volume of water of the mixed medicinal materials, and decocted for 50 minutes. Continue to add rice wine with 5 times the volume of the mixed medicinal materials, and continue to cook for 10 minutes, for a total of 1 hour. Repeat the above steps twice, combine the medicinal solutions obtained twice, pass through a 200-mesh sieve, and concentrate to a density of 1.10 and a solid content of 20% to obtain concentrated solution A.

[0091] Step 2: Take 90 parts of concentrated solution A, add 10 parts of the first auxiliary material, pass through a colloid mill to mix evenly, pa...

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Abstract

The invention relates to a moisture-proof five-ingredient detoxication drink granules and a preparation method thereof. According to the moisture-proof five-ingredient detoxication drink granules, flos lonicerae, chrysanthemum indicum linn, dandelions, herba violae and radix semiaquilegiae are decocted to obtain a decoction concentrated solution A, a first auxiliary material is added into the decoction concentrated solution A and uniformly mixed through a colloid mill, spray drying is performed to obtain a spray drying material B, finally a second auxiliary material is added into the spray drying material B, stirring and mixing are performed, and dry granulation is performed, the moisture-proof five-ingredient detoxication drink granules are prepared, the first auxiliary material comprises copovidone S630, beta-cyclodextrin and maltodextrin, and the second auxiliary material comprises dextrin, lactose and soluble starch. The five-ingredient detoxication drink granules have good moisture resistance and good stability.

Description

technical field [0001] The invention relates to the technical field of preparation of traditional Chinese medicine granules, in particular to a moisture-proof Wuwei Xiaoxiaoyin granule and a preparation method thereof. Background technique [0002] Wuwei Xiaoxiaoyin Granules originated from Volume 72 of "Jinjian of Medicine • Essentials of Surgical Heart Method", which is a classic prescription of the Qing Dynasty. Specifically, Wuwei Xiaoduyin granules have the functions of clearing away heat and detoxifying and dissipating sores. In modern clinic, it is mainly used for skin purulent infection, itching, boils and antiviral diseases. [0003] "Five-flavored disinfection drink" is a classic and famous prescription preparation. It is a prescription formulated by the State Administration of Traditional Chinese Medicine and the State Drug Administration in accordance with the "Chinese Medicine Law of the People's Republic of China". The prescription was initially identified as...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/86A61K9/16A61K47/32A61K47/40A61K47/36A61K47/26A61P29/00A61P17/02A61P31/04A61P17/04A61P31/12
CPCA61K36/355A61K36/288A61K36/287A61K36/86A61K36/71A61K9/1682A61K9/1635A61K9/1652A61K9/1623A61P29/00A61P17/02A61P31/04A61P17/04A61P31/12A61K2236/331A61K2236/39A61K2236/51A61K2236/333A61K2300/00Y02A50/30
Inventor 罗晓健刘文君张尧季巧遇饶小勇孙函静张爱玲吴样明
Owner JIANGZHONG PHARMA
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