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A kind of traditional Chinese medicine composition for treating liver disease and its preparation method and application

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating liver disease and its preparation field, can solve the problems of uneven treatment effect, difficult to obtain the expected curative effect, etc., and achieve the effect of increasing HDL content and improving pathological symptoms

Active Publication Date: 2022-05-10
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many prescriptions for this treatment method, but the therapeutic effect is uneven, and because of the differences between ancient and modern times, it is difficult to obtain the expected curative effect by using some ancient prescriptions directly.

Method used

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  • A kind of traditional Chinese medicine composition for treating liver disease and its preparation method and application
  • A kind of traditional Chinese medicine composition for treating liver disease and its preparation method and application
  • A kind of traditional Chinese medicine composition for treating liver disease and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Embodiment 1 A kind of Chinese medicine composition for the treatment of liver disease

[0059] 1. A Chinese medicine composition for treating liver disease, said Chinese medicine composition is prepared from the following raw materials in parts by weight: Bupleurum: 10 parts, Fried Atractylodes Rhizoma Atractylodes Rhizome: 20 parts, Capillary Rhizome: 15 parts, Alisma: 10 parts , Weeping grass: 25 parts, Danshen: 10 parts, red peony: 10 parts, raw hawthorn: 20 parts, fried Citrus aurantium: 10 parts, artificial bezoar: 0.1 parts.

[0060] 2. A preparation method of a Chinese medicine composition for the treatment of liver disease, comprising the steps of:

[0061] (1) Take Bupleurum: 10g, fried Atractylodes macrocephala: 20g, capillary: 15g, Alisma: 10g, weeping grass: 25g, salvia: 10g, red peony: 10g, raw hawthorn: 20g, fried aurantium: 10g, Artificial bezoar: 0.1g, chop the above raw materials (except artificial bezoar): rhizomes (bupleurum, fried Atractylodes macr...

Embodiment 2

[0062] Embodiment 2 A kind of Chinese medicine composition for the treatment of liver disease

[0063] 1. A Chinese medicine composition for treating liver disease, said Chinese medicine composition is prepared from the following raw materials in parts by weight: Bupleurum: 10 parts, Fried Atractylodes Rhizoma Atractylodes Rhizome: 15 parts, Capillary Rhizome: 15 parts, Alisma: 10 parts , Weeping grass: 30 parts, Danshen: 10 parts, red peony: 10 parts, raw hawthorn: 20 parts, fried Citrus aurantium: 10 parts, artificial bezoar: 0.1 parts.

[0064] 2. A preparation method of a Chinese medicine composition for the treatment of liver disease, comprising the steps of:

[0065] (1) Chop the above raw materials (except artificial bezoar): rhizomes (bupleurum, fried Atractylodes macrocephala, Alisma, red sage root, red peony root) to 2 minutes thick, whole herbs (capillary, weeping grass) to 5 minutes Divide into thickness, cut fruits (raw hawthorn, fried Citrus aurantium) to 1 min ...

Embodiment 3

[0066] Embodiment 3 a kind of Chinese medicine composition for the treatment of liver disease

[0067] 1. A Chinese medicine composition for treating liver disease, said Chinese medicine composition is prepared from the following raw materials in parts by weight: Bupleurum: 15 parts, Fried Atractylodes Rhizoma Atractylodes Rhizome: 15 parts, Capillary Rhizome: 15 parts, Alisma: 15 parts , Weeping grass: 25 parts, Danshen: 10 parts, red peony root: 10 parts, raw hawthorn: 20 parts, fried Citrus aurantium: 15 parts, artificial bezoar: 0.1 part.

[0068] 2. A preparation method of a Chinese medicine composition for the treatment of liver disease, comprising the steps of:

[0069] (1) Chop the above raw materials (except artificial bezoar): rhizomes (bupleurum, fried Atractylodes macrocephala, Alisma, red sage root, red peony root) to 1 minute thick, whole herbs (capillary wormwood, weeping grass) to 3 Cut the fruits (raw hawthorn, fried Citrus aurantium) to 0.5 minutes thick; pu...

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Abstract

The invention belongs to the field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating liver diseases, a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials: Bupleurum, Atractylodes macrocephala, capillary, Alisma, weeping grass, salvia, red peony, hawthorn, citrus aurantium and bezoar; the traditional Chinese medicine composition can significantly reduce liver quality, liver Index, visceral fat mass, body fat percentage; reduce serum AST, ALT, TG, TC, LDL and FFA content, increase HDL content; reduce liver tissue and serum inflammatory factors IL-1β, IL-6 and TNF-α content ; reduce the content of TG and TC in liver tissue; improve the symptoms of hepatitis; and have no significant effect on body weight, that is, no side effects; it can be used to treat liver diseases.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating liver diseases, a preparation method and application thereof. Background technique [0002] With lifestyle changes and the prevalence of obesity, non-alcoholic fatty liver disease (NAFLD) has become the world's No. 1 chronic liver disease, with an incidence rate as high as 25%. Among them, non-alcoholic steatohepatitis (NASH) is a very harmful stage in the NAFLD disease spectrum, which can lead to the occurrence of liver cirrhosis and liver cancer, and is one of the main reasons for end-stage liver disease and liver transplantation. [0003] At present, the treatment of NAFLD and NASH mainly adopts lifestyle intervention therapy, such as dietary calorie restriction and exercise, etc. However, this therapy is difficult to maintain and the effect is not good for some patients, so the development of new d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/884A61P1/16A61P29/00A61K35/413
CPCA61K36/233A61K36/284A61K36/282A61K36/884A61K36/41A61K36/537A61K36/71A61K36/65A61K36/734A61K36/752A61K35/413A61P1/16A61P29/00A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00
Inventor 程发峰王雪茜马重阳吉静邵奇
Owner BEIJING UNIV OF CHINESE MEDICINE
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