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Microwave ablation area defining method based on tissue reduction scattering coefficient

A technology of reducing scattering coefficient and microwave ablation, which is applied in microwave surgical instruments, parts of surgical instruments, medical science, etc., and can solve the problem that the ablation boundary cannot be defined.

Active Publication Date: 2021-09-28
NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] In order to solve the problem that the ablation boundary cannot be defined at present, the present invention proposes a real-time evaluation method for microwave ablation tissue Young's modulus based on the reduced scattering coefficient, which realizes the quantitative relationship definition between the reduced scattering coefficient and the ablation area

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  • Microwave ablation area defining method based on tissue reduction scattering coefficient
  • Microwave ablation area defining method based on tissue reduction scattering coefficient
  • Microwave ablation area defining method based on tissue reduction scattering coefficient

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Embodiment 1

[0031] A method for defining the microwave ablation area based on tissue reduced scattering coefficient, in the process of microwave ablation according to the tissue reduced scattering coefficient s Realize real-time curative effect assessment and define the boundaries of the ablation area, including the following steps:

[0032] S1. Build a near-infrared spectrum acquisition and microwave ablation system;

[0033] The microwave ablation system for collecting near-infrared optical parameters built in step S1 includes: a microwave ablation module, a reduced scattering coefficient measurement module, and a data acquisition and storage module. The microwave ablation module includes a microwave ablation instrument 7, an isolated pig liver 5, and an ablation needle 6; the temperature and appointment scattering coefficient measurement module includes an optical fiber probe 1, a near-infrared light source 2, and an optical fiber spectrometer 4; the data acquisition and The storage s...

Embodiment 2

[0043] Such as figure 1 As shown, a microwave ablation area definition method based on the reduced scattering coefficient of the tissue realizes real-time curative effect evaluation according to the reduced scattering coefficient of the tissue during the microwave ablation process, and defines the boundary of the ablation area, including the following steps:

[0044] S1. Build a near-infrared spectrum acquisition and microwave ablation system;

[0045] S2. Ablation and near-infrared spectroscopy data collection;

[0046] S3. Acquiring near-infrared optical parameters of different areas of microwave ablation;

[0047] S4. A microwave ablation area definition model based on the reduced scattering coefficient is established;

[0048] S5. Model verification.

[0049] Such as figure 2 It is a schematic diagram of an isolated pig liver microwave ablation and near-infrared optical parameter acquisition device involved in a tissue-reduced scattering coefficient-based microwave ab...

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Abstract

The invention discloses a microwave ablation area defining method based on a tissue reduction scattering coefficient. According to the invention, scattering characteristic changes of liver tissues in a microwave ablation heat injury process and correlation between the scattering characteristic changes and tissue damage degrees are quantitatively analyzed by measuring near infrared spectrum and optical characteristics of ex-vitro porcine liver tissues before and after microwave ablation for the first time, a diffuse reflection spectrum is adopted to calculate reduced scattering coefficients, distribution characteristics of the reduced scattering coefficients of the tissues in different ablation areas after microwave ablation are analyzed to find that the reduced scattering coefficients are closely associated with ablation damage degrees, and the reduced scattering coefficients of the tissues in the different areas have respective fixed numerical values, on the base of which microwave ablation area defining models based on the reduced scattering coefficients are established. According to the method, minimally invasive real-time curative effect evaluation in a microwave ablation operation can be realized, and the method has an important value for clinical microwave ablation treatment effect evaluation and ablation boundary definition.

Description

technical field [0001] The present invention relates to the technical field of microwave ablation curative effect evaluation, in particular to a method for defining microwave ablation regions based on tissue reduced scattering coefficients Background technique [0002] Microwave ablation is one of the important methods for treating tumors today, and has achieved good clinical results. It is a rapidly developing new tumor treatment technology that has played an important role in clinical practice. However, microwave ablation is currently invisible due to its invisibility. , so the judgment of intraoperative curative effect and ablation boundary often relies on the operating experience of the operating doctor, and there are certain safety hazards in the ablation process, so it is necessary to find effective parameters that can correctly determine the definition of the ablation boundary, so that it can be reflected in the ablation process Tumor ablation status. [0003] The op...

Claims

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Application Information

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IPC IPC(8): A61B18/18G01N21/3563G01N21/359
CPCA61B18/1815G01N21/3563G01N21/359
Inventor 冯宇朱柔君吴鑫钱志余李梦雪张丹俞钦栋唐千舜
Owner NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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