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ACE2 protein biochip, preparation method and application thereof

A biochip and protein technology, applied in biological testing, material inspection products, measuring devices, etc., can solve problems such as time-consuming and cumbersome operation process

Pending Publication Date: 2021-10-08
THE SECOND AFFILIATED HOSPITAL OF NANJING MEDICAL UNIV
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0002] Nucleic acid detection method is an important detection method for epidemic viruses at present, but when the number of detection samples is large, the operation process of nucleic acid detection method is cumbersome and time-consuming, which causes a lot of inconvenience

Method used

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  • ACE2 protein biochip, preparation method and application thereof
  • ACE2 protein biochip, preparation method and application thereof
  • ACE2 protein biochip, preparation method and application thereof

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Embodiment Construction

[0020] The following will clearly and completely describe the technical solutions in the embodiments of the present disclosure with reference to the accompanying drawings in the embodiments of the present disclosure. Apparently, the described embodiments are only some of the embodiments of the present disclosure, not all of them. Based on the embodiments in the present disclosure, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present disclosure.

[0021] In one example of the present disclosure, such as figure 1 As shown, a biological chip may include a support, a metal film and ACE2 protein. In this example, the support is a glass slide. Wherein, the metal film is attached to the glass slide, and the surface of the metal film is coated with mercapto-oligoethylene glycol and mercapto-oligoethylene glycol carboxylic acid to form a hydrophilic film; then the ACE2 protein is connected to the...

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Abstract

The invention discloses an ACE2 protein biochip, a preparation method and application thereof, and belongs to the field of biochips. The biochip comprises a support substance, a metal film and ACE2 protein, wherein the metal film and the ACE2 protein are attached to the surface of the support substance, the surface of the biochip is coated with sulfydryl oligo-polyethylene glycol and sulfydryl oligo-polyethylene glycol carboxylic acid to form a hydrophilic film, and the ACE2 protein is connected to the support substance through an amido bond.

Description

technical field [0001] The examples of the present disclosure relate to the field of biochips, in particular to an ACE2 protein biochip and its preparation method and application. Background technique [0002] Nucleic acid detection method is an important detection method for epidemic viruses at present, but when the number of detection samples is large, the operation process of nucleic acid detection method is cumbersome and time-consuming, which causes a lot of inconvenience. Contents of the invention [0003] Aiming at the deficiencies of the prior art, the present disclosure proposes an ACE2 protein biochip and its preparation method and application. [0004] The purpose of this disclosure can be achieved through the following technical solutions: [0005] A biochip comprising: [0006] support; [0007] A metal film attached to the surface of the support, the surface of which is coated with mercapto-oligoethylene glycol and mercapto-oligoethylene glycol carboxylic ...

Claims

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Application Information

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IPC IPC(8): G01N33/68
CPCG01N33/6893
Inventor 张业伟卿鑫
Owner THE SECOND AFFILIATED HOSPITAL OF NANJING MEDICAL UNIV
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