Pancreaticobiliary ampulla carcinoma classification model generation method and image classification method

Abstract

The invention discloses a pancreaticobiliary ampulla carcinoma classification model generation method and an image classification method. The model generation method comprises the steps of constructing an initial classification model, wherein the initial classification model comprises an image preprocessing module, a cell segmentation module, a cell morphological feature extraction module and a classification module; labeling the collected bile duct cancer pathological sections and pancreatic cancer pathological sections to form a digital pathological image labeling library; dividing the digital pathological image annotation library into training set data and test set data according to a preset proportion, wherein the training set data comprises a bile duct cancer pathological section and a pancreatic cancer pathological section which are subjected to annotation processing; and training the initial classification model by adopting the training set data, and completing parameter adjustment of the initial classification model to obtain the pancreatic duct type ampullaria carcinoma classification model. According to the method, a classification model is constructed based on a full-slice digital pathological image of HE staining for the first time to perform subtype classification on pancreatic duct type peripheral ampulla cancer; that is, whether a tumor originates from a pancreatic duct (pancreatic cancer) or a bile duct (bile duct cancer) is judged.

Description

technical field [0001] The invention relates to the technical field of image recognition, in particular to a method for generating a classification model of pancreaticobiliary ampullary carcinoma and an image classification method. Background technique [0002] Periampullary carcinoma (vater ampulla carcinoma, VPC) refers to tumors in the ampulla of Vater, the lower end of the common bile duct, the opening of the pancreatic duct, the duodenal papilla and the adjacent duodenal mucosa. The position of the ampulla is as figure 1 As shown, it is divided into pancreatic head cancer, pancreatic common bile duct cancer, ampullary cancer and duodenal cancer, and the latter three can be collectively referred to as ampullary cancer. Survival varies widely among patients with periampullary cancers that have traditionally been classified according to their anatomical location of origin, ie duodenum, ampulla, distal common bile duct, or pancreatic head. However, they can be alternately...

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Problems solved by technology

[0005] In view of the above-mentioned deficiencies in the prior art, the purpose of the present invention is to provide a method for generating a classification model of pancreaticobiliary ampullary carcinoma and an image classification method, aiming at solving the problem that the prior art cannot realize automatic pathological section analysis of pancreaticobiliary ampulla carcinoma. Questions for further subtyping

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