Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of cyclosporine A in preparation of medicine for improving embryo implantation rate of patient suffering from repeated embryo implantation failure

A technology of implantation failure and cyclosporine, applied in drug combination, cyclic peptide components, diseases, etc., can solve the problems of lack of CsA treatment effect and lack of evidence-based medical evidence of cyclosporine

Active Publication Date: 2021-12-10
SUZHOU MUNICIPAL HOSPITAL
View PDF6 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since 2005, there have been 13 diagnostic criteria for RIF. At present, the definition of RIF has not been unified, and there are disputes in terms of the number of embryo transfer cycles, the number and quality of transfer embryos, the stage and cycle type of transfer embryos, and age.
At present, there is still a lack of therapeutic effect of CsA in patients with embryo implantation failure, and the application of cyclosporine in the field of reproduction is still lacking in evidence-based medicine

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of cyclosporine A in preparation of medicine for improving embryo implantation rate of patient suffering from repeated embryo implantation failure
  • Application of cyclosporine A in preparation of medicine for improving embryo implantation rate of patient suffering from repeated embryo implantation failure
  • Application of cyclosporine A in preparation of medicine for improving embryo implantation rate of patient suffering from repeated embryo implantation failure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0017] The invention discloses the application of cyclosporine A in the preparation of medicine for improving the implantation rate of embryos in patients with repeated embryo implantation failures. The present invention points out for the first time that cyclosporine A can significantly improve the embryo implantation rate of patients with repeated embryo implantation failures; different from pregnancy or post-pregnancy abortion, in vitro fertilization-embryo transplantation into the mother's uterus is a different step and is affected by different factors.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses application of cyclosporine A in preparation of a medicine for improving the embryo implantation rate of a patient suffering from repeated embryo implantation failure. In the prior art, the cyclosporine A is used as an immunosuppressor or a medicine for preventing miscarriage and preventing abortion, the application proposes that the cyclosporine A can improve the embryo planting rate for the first time, and particularly discloses improvement of the embryo planting rate of secondary embryo transplantation of the patient suffering from the repeated embryo implantation failure, and the research result is different from that in the prior art. Specifically, according to the technical scheme, clinical application of the cyclosporine A can be effectively guided, and side effects caused by improper medication are avoided.

Description

technical field [0001] The invention belongs to in vitro fertilization-embryo transplantation derivative technology, and specifically relates to the application of cyclosporin A in the preparation of medicines for improving the implantation rate of embryos in patients with repeated embryo implantation failures. Background technique [0002] Fertility disorders affect about 18-20% of couples of childbearing age in my country, becoming the third largest category of diseases after cancer and cardiovascular and cerebrovascular diseases. In recent years, the level of ART has been improved and developed. The clinical pregnancy rate of In vitro fertilization-embryo transfer (IVF-ET) has increased to 50-60%, but the embryo implantation rate is still hovering at 30-40%. At present, the failure of embryo implantation is the bottleneck that restricts the further improvement of ART clinical pregnancy rate and live birth rate, and also brings great economic and mental pressure to patient...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/13A61P15/08
CPCA61K38/13A61P15/08
Inventor 朱蕊李红李大金杜美蓉李明清
Owner SUZHOU MUNICIPAL HOSPITAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com