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Portulaca oleracea composite sugar-controlling tablet and preparation method thereof

A technology of purslane and sugar tablets, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, can solve problems such as large doses, hypoglycemia, edema, etc., and relieve complications, pain, crude polysaccharide high content effect

Pending Publication Date: 2022-04-26
CHANGCHUN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commonly used blood sugar control methods, in addition to drug control, auxiliary hypoglycemic health food control has also become one of the commonly used methods for people, and long-term use of drugs will lead to drug resistance, and the side effects are more obvious when taken in large doses or for a long time (such as : Thiazolidine can reduce and improve glucose tolerance in obese patients with insulin resistance, but it will cause edema and hypoglycemia; Baisupine mainly reduces postprandial hyperglycemia and relieves hyperinsulinemia, but it will cause gastrointestinal tract reaction)

Method used

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  • Portulaca oleracea composite sugar-controlling tablet and preparation method thereof
  • Portulaca oleracea composite sugar-controlling tablet and preparation method thereof
  • Portulaca oleracea composite sugar-controlling tablet and preparation method thereof

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Embodiment Construction

[0029] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. The specific embodiments described here are only used to explain the present invention, not to limit the invention.

[0030] A purslane composite sugar-controlling tablet is made of the following raw materials in weight percentage:

[0031] Purslane, bitter melon, Radix Astragali, Atractylodes atractylodis (weight ratio is 1.5:1:1:1) 25.1%, chromium picolinate 0.1%, disintegrant (low-substituted hydroxypropyl cellulose L-HCP and carboxy Sodium methyl starch CMS-Na (1:2 weight ratio) 35%, filler (microcrystalline cellulose and dextrin weight ratio is 7:1) 38.8%, magnesium stearate 1%, concentration 10% Alcohol solution of polyvinylpyrrolidone PVP.

[0032] The preparation process is specifically:

[0033] 1) Dry the purslane at 55°C to constant weight, crush it with a tissu...

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Abstract

The invention discloses a purslane compound sugar-controlling tablet and a preparation method thereof. The purslane compound sugar-controlling tablet is prepared from the following raw materials in percentage by weight: 25.1% of a main drug consisting of purslane, bitter gourd, astragalus membranaceus and rhizoma atractylodis, 0.1% of chromium picolinate, 35% of a disintegrating agent, 38.8% of a filling agent and 1% of a lubricating agent. Compared with the prior art, portulaca oleracea, balsam pear, astragalus membranaceus and atractylodes lancea are combined and matched with a trace amount of chromium picolinate (organic chromium element (trivalent chromium) has the effects of activating insulin, enabling the utilization rate of edible sugar to be high or enabling the edible sugar to be more converted and controlling blood sugar rise) with a specific blood sugar reducing effect; meanwhile, a filling agent, an adhesive and a disintegrating agent are combined to prepare the sugar control tablet convenient to carry, and the sugar control tablet is high in crude polysaccharide content, so that the sugar control tablet has a very good auxiliary blood sugar reducing effect; the invention provides a theoretical basis for deeply researching the hypoglycemic effects of the purslane, the bitter gourd, the astragalus membranaceus and the atractylodes lancea and developing new auxiliary hypoglycemic health-care products, and has important significance for relieving complications of diabetic patients.

Description

technical field [0001] The invention relates to the field, in particular to a compound sugar-controlling tablet of purslane and a preparation method thereof. Background technique [0002] Diabetes mellitus is a group of metabolic diseases characterized by chronic hyperglycemia caused by multiple etiologies, which is caused by defects in insulin secretion and (or) utilization. Long-term carbohydrate, fat, and protein metabolic disorders can cause multi-system damage, leading to chronic progressive lesions, functional decline, and failure of the eyes, kidneys, nerves, heart, blood vessels, and other tissues and organs. Acute severe metabolic disorders, such as diabetic ketoacidosis and hyperosmolar hyperglycemia syndrome, can occur in severe illness or stress. The number of people with diabetes in the world will reach 330 million by 2025, and 90%-95% are non-insulin-dependent diabetes. A large number of hypoglycemic drugs are in clinical application, but they have large side...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61K9/20A61P3/10A23L33/125A23L33/10A23L19/00A23P10/28A61K31/555
CPCA61K36/185A61K36/42A61K36/481A61K36/284A61K31/555A61K9/2059A61P3/10A23L33/125A23L33/10A23L19/01A23P10/28A61K2236/35A61K2236/39A61K2236/333A61K2236/51A61K2236/331A61K2236/53A23V2002/00A61K2300/00A23V2200/328A23V2250/51084A23V2250/5114A23V2250/51088
Inventor 张海悦武旭明闫小娟许家豪
Owner CHANGCHUN UNIV OF TECH
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