Radiotherapy treatment planning using microdose functions

A technology of treatment planning and dose, applied in the direction of treatment, radiation therapy, mechanical/radiation/invasive treatment, etc., which can solve the problems of increased complexity

Active Publication Date: 2022-04-29
医科达股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This task can be a time-consuming trial-and-error process that is complicated by the variety of OARs, as the complexity of the process increases as the number of OARs increases (for exam...

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  • Radiotherapy treatment planning using microdose functions
  • Radiotherapy treatment planning using microdose functions
  • Radiotherapy treatment planning using microdose functions

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Embodiment Construction

[0024] The present disclosure includes various techniques for generating radiotherapy treatment plans by using machine learning (ML) models or solving optimization problems based on derivatives of dose calculations. As an example, a ML model can be trained to estimate one or more parameters of radiotherapy treatment planning from radiotherapy treatment planning information (eg, CT images or MR images) based on a loss function that considers the derivative of dose (e.g., synthetic CT images) . As another example, one or more parameters of the optimization problem (e.g., constraints and / or decision variables) may take into account derivatives of the dose to generate a solution to the optimization problem, thereby providing one or more parameters of the radiotherapy treatment plan (e.g., , radiotherapy device parameters or control points). Technical benefits include reduced computational processing time for generating radiotherapy treatment plans and solving radiotherapy treatme...

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Abstract

Techniques for generating radiotherapy treatment plan parameters are provided. The technology comprises the following steps: receiving radiotherapy treatment plan information; processing the radiotherapy treatment plan information to estimate one or more radiotherapy treatment plan parameters based on processing of an output of the sub-processing dependent on the derivative of the estimated dose calculation; and generating a radiotherapy treatment plan using the estimated one or more radiotherapy treatment plan parameters.

Description

[0001] priority claim [0002] This application claims the benefit of priority to US Application Serial No. 16 / 512,938, filed July 16, 2019, which is incorporated herein by reference in its entirety. technical field [0003] The present disclosure generally relates to generating radiation therapy or radiotherapy treatment plans. Background technique [0004] Radiation therapy is used to treat cancer and other diseases in mammalian (eg, humans and animals) tissues. The direction and shape of the radiation beam should be precisely controlled to ensure that the tumor receives the prescribed radiation, and the beam should be placed so as to minimize damage to surrounding healthy tissue (often referred to as organ at risk (OAR)). A treatment plan can be used to control radiation beam parameters, and a radiation therapy device achieves treatment by delivering a spatially varying dose distribution to the patient. [0005] Traditionally, for each patient, optimization techniques c...

Claims

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Application Information

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IPC IPC(8): A61N5/10G16H20/40G16H50/20G06N20/00
CPCA61N5/103A61N5/1039A61N5/1031G16H50/20G16H20/40A61N2005/1034G06N20/00G06N3/084
Inventor 延斯·舍隆德
Owner 医科达股份有限公司
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