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Chromosome straightening method and device, computer equipment and storage medium

A chromosome and computer program technology, applied in the field of computer technology and image processing, can solve the problem of low accuracy and achieve the effect of improving accuracy

Pending Publication Date: 2022-06-03
SHENZHEN REETOO BIOTECHNOLOGY CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, it has been observed that the centromere is not necessarily the bending center of the chromosome, which leads to the inaccuracy of this method of using the centromere as the bending center for chromosome straightening

Method used

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  • Chromosome straightening method and device, computer equipment and storage medium
  • Chromosome straightening method and device, computer equipment and storage medium
  • Chromosome straightening method and device, computer equipment and storage medium

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Embodiment Construction

[0050] In order to make the objectives, technical solutions and advantages of the present application more clear, the present application will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application, but not to limit the present application.

[0051] In one embodiment, as figure 1 As shown, a chromosome straightening method is provided. In this embodiment, the method is applied to a terminal as an example. It can be understood that the method can also be applied to a server, and can also be applied to a system including a terminal and a server. Through the interaction between the terminal and the server. In this embodiment, the method includes the following steps:

[0052] S102, perform binarization processing on the chromosome image to obtain a binary image of the chromosome.

[0053] The chromosome image is an im...

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Abstract

The invention relates to a chromosome straightening method and device, computer equipment and a storage medium. The method comprises the following steps: carrying out binarization processing on a chromosome image to obtain a binary image of a chromosome; performing skeleton extraction on the binary image; determining a positive rotation angle of the chromosome according to the extracted skeleton; correcting the chromosome in the binary image according to the correcting angle to obtain a corrected image; determining the bending center of the chromosome according to the horizontal projection vector of each row in the corrected image; and carrying out straightening processing on the chromosome in the chromosome image by taking the bending center as a reference. By adopting the method, the accuracy of chromosome straightening can be improved.

Description

technical field [0001] The present application relates to the field of computer technology and image processing technology, and in particular, to a chromosome straightening method, device, computer equipment and storage medium. Background technique [0002] In chromosome karyotype analysis, it is often necessary to process and analyze chromosome images. However, due to differences in chromosome development, longer chromosomes often bend during development, which makes karyotype analysis more difficult. Therefore, it is very important to straighten the chromosomes in the chromosome image. [0003] In the traditional method, the centromere of the chromosome in the chromosome image is generally determined as the bending center, and then the chromosome arms on both sides of the centromere are rectified with the centromere as the center to achieve chromosome straightening. However, it has been observed that the centromere is not necessarily the bending center of chromosomes, re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T5/00G06T7/64
CPCG06T7/64G06T2207/20068G06T5/80Y02A10/40
Inventor 许德鹏刘晓康王雪峰陈齐文
Owner SHENZHEN REETOO BIOTECHNOLOGY CO LTD
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