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Anti-wrinkle repairing composition, preparation method thereof and cosmetic containing anti-wrinkle repairing composition

The technology of a composition and its derivatives is applied in the field of anti-wrinkle repair composition and its preparation method and the cosmetics containing the composition, which can solve the problems of microemulsion safety hazards and other problems, and achieve the goal of improving softness and smoothness and accelerating renewal speed Effect

Pending Publication Date: 2022-06-24
GUANGDONG MARUBI BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, a large amount of small molecule surfactants will be used in the preparation of microemulsions, and high concentrations of surfactants will cause hemolytic toxicity, so the application of microemulsions often has potential safety hazards

Method used

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  • Anti-wrinkle repairing composition, preparation method thereof and cosmetic containing anti-wrinkle repairing composition
  • Anti-wrinkle repairing composition, preparation method thereof and cosmetic containing anti-wrinkle repairing composition
  • Anti-wrinkle repairing composition, preparation method thereof and cosmetic containing anti-wrinkle repairing composition

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preparation example Construction

[0040] The preparation method of the above-mentioned anti-wrinkle repair composition comprises the following steps:

[0041] 1) Dissolve 1 g of chitosan in 100 mL of acetic acid aqueous solution with a concentration of 1%, add 100 mL of methanol solution to dilute, add 0.95 g of linoleic acid to the above solution, stir at 20 ~ 25 ° C for 5 minutes, and then dropwise add 15mL of methanol solution of 1-ethyl-(3-dimethylaminopropyl)carbodiimide (EDC) with a concentration of 0.05g / L was reacted at 20-25°C for 24h, and the reaction mixture was poured into mass Stir in a methanol / aqueous ammonia mixed solution with a ratio of 7:3, filter, take the precipitate, wash it with distilled water, methanol and diethyl ether in turn, and vacuum dry it at 20-5 °C for 12 hours to obtain solid granular linoleic acid-modified Chitosan; wherein, the molar ratio of 1-ethyl-(3-dimethylaminopropyl)carbodiimide to chitosan is approximately equal to 1:1;

[0042] 2) Dilute the linoleic acid-modified...

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Abstract

The invention discloses an anti-wrinkle repairing composition and a preparation method thereof and a cosmetic containing the composition, the preparation method of the anti-wrinkle repairing composition comprises the following steps: firstly preparing colloidal granular linoleic acid modified chitosan, then dissolving the obtained linoleic acid modified chitosan in water, and then adding a water-soluble skin conditioner to obtain a water phase; the preparation method comprises the following steps: preparing a water phase, dissolving vitamin A and / or a vitamin A derivative in grease to form an oil phase, mixing and emulsifying the water phase and the oil phase to obtain a Pickering emulsion, and loading the vitamin A and / or the vitamin A derivative through linoleic acid modified chitosan, so that the vitamin A and / or the vitamin A derivative can be prevented from losing efficacy due to the influence of an external environment; the release of the vitamin A and / or the vitamin A derivative can be controlled, so that the effects can be better exerted. The composition can be used as one of raw materials of cosmetics, and the Pickering emulsion has better compatibility and stability and can be used for constructing multi-effect cosmetics.

Description

technical field [0001] The present invention relates to the technical field of cosmetics, in particular to an anti-wrinkle repair composition, a preparation method thereof, and a cosmetic comprising the composition. Background technique [0002] Vitamin A is a fat-soluble vitamin, also known as retinol. It is an essential vitamin to keep the skin epithelial tissue healthy, but it contains many unsaturated bonds in its structure, so vitamin A is very sensitive to visible light, ultraviolet light, oxygen, etc. . The application of retinol in cosmetic formulations also has limitations (such as retinol is easily oxidized in the air, easily deactivated under ultraviolet radiation, insoluble in water, etc.), and the irritation and instability of retinol limit its use. The amount of retinol added in cosmetics also causes the excellent anti-aging and acne-removing effects of retinol to not be fully exerted. [0003] In order to improve the solubility, stability and permeability of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/36A61K8/67A61K8/06A61K8/9794A61K8/9789A61K8/65A61Q19/08A61Q19/00A61Q17/00
CPCA61K8/736A61K8/361A61K8/671A61K8/06A61K8/73A61K8/9794A61K8/9789A61K8/65A61Q19/08A61Q19/00A61Q17/005A61K2800/5922A61K2800/782A61K2800/78
Inventor 孙云起佐佐木公夫胡露郭朝万王宁
Owner GUANGDONG MARUBI BIOLOGICAL TECH CO LTD
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