Equipment and method for measuring autofluorescence of glass material

Abstract

The invention discloses glass material autofluorescence measurement equipment and a glass material autofluorescence measurement method. The glass material autofluorescence measurement equipment comprises a light source module, an autofluorescence collection module, an autofluorescence measurement module and a black box module. The light source module comprises a laser and a collimating lens; the autofluorescence collecting module comprises a first excitation optical filter, glass to be detected, a second excitation optical filter, a first light collecting mirror, a reflecting mirror, a second light collecting mirror and a collecting mirror, and is used for collecting and converging autofluorescence generated by the glass to be detected; the autofluorescence measurement module comprises a photon measurement device, and the photon measurement device is located at the focus of the collecting lens and used for measuring autofluorescence converged by the collecting lens; and the autofluorescence collection module and the autofluorescence measurement module are placed in the black box module. By adopting the glass material autofluorescence measurement equipment provided by the invention, most of autofluorescence of the glass to be measured can enter the measurement system through the light collecting mirror, so that the accuracy of autofluorescence measurement is ensured.

Description

technical field [0001] The invention relates to the technical field of optical precision measurement, in particular to a device and method for measuring the autofluorescence of glass materials. Background technique [0002] For advanced cancers, effective treatment is difficult, therefore, in situ detection of these cancers or dysplasias is required at the early stage of their progression. Currently, the most widely used method of early detection is through endoscopy. During endoscopy, the tissue is illuminated with light of the appropriate wavelength and the resulting fluorescence is observed. Fluorescence produced by tissue is generally of longer wavelength than the excitation illumination light and is usually very weak, so spectroscopic techniques are often used to observe fluorescence produced by tissue. [0003] There are usually two methods of using fluorescence information for diagnosis. The first method is to inject photosensitizers into patients, using the differe...

AI Technical Summary

Problems solved by technology

However, when these optical devices transmit the irradiated light, they are likely to generate autofluorescence due to the irradiated light. If the autofluorescence band coincides with the autofluorescence band produced by the tissue to be measured, it will have a greater impact on the measurement results.

In actual use, most optical devices are made of glass, but there is no corresponding autofluorescence information in the current glass material manual. Therefore, the influence of optical devices on autofluorescence is still unknown. The autofluorescence of glass is relatively weak, and even a small noise may affect the judgment of diseased tissue. If the influence of glass autofluorescence is not considered in the actual use process, there may be a high false negative problem, which cannot be used as a diagnosis. in accordance with

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