Marker and model construction method and system for prognosis prediction of colon cancer

A technology of colon cancer and markers, applied in the field of biomedicine, can solve the problem of few reports on the prognosis risk assessment of colon cancer patients, and achieve high prognosis prediction accuracy
CN114863993AActive Publication Date: 2022-08-05臻和(北京)生物科技有限公司 +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
臻和(北京)生物科技有限公司
Publication Date
2022-08-05

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Abstract

The invention relates to the technical field of biological medicine, in particular to a marker for prognosis prediction of colon cancer, and a model construction method and system. According to the TLS-related quantitative index for prognosis prediction of the colon cancer patient, the TLS-related quantitative index is used as a marker for prognosis prediction of the colon cancer, the immune state of the patient can be reflected more accurately and objectively, and higher prognosis prediction accuracy is achieved. The invention further provides a colon cancer prognosis risk model and a construction method thereof, the model can carry out prognosis prediction independent of TNM staging, prognosis risk layering can be better carried out on colon cancer patients compared with TNM staging, more targeted treatment schemes can be made for patients with different prognosis clinically, and precise medical treatment can be achieved.
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Description

technical field

[0001] The present invention relates to the technical field of biomedicine, in particular to a marker, a model construction method and a system for predicting the prognosis of colon cancer. Background technique

[0002] Colon cancer is one of the most common malignant tumors in the world, and its incidence and mortality ranks among the top three among all malignant tumors. The overall survival rate of colon cancer patients depends on the TNM staging of the tumor. TNM is a form of tumor staging in oncology. It is mainly determined according to the tumor infiltration, the number of lymph nodes and whether it has metastasized to other parts. The higher the degree of tumor progression, the worse the prognosis. According to the American Joint Committee on Cancer, the 5-year survival rates of patients with stage I, II, III and IV colon cancer were 93.2%, 82.5%, 59.5% and 8.1%, respectively. However, in clinical practice, there are often significant differences in...

Claims

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