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Medicinal composition, its preparation method and use

A composition and drug technology, applied in the direction of drug combination, drug delivery, drug formulation, etc., to achieve the effects of improving symptoms, enhancing immune function, and enhancing their respective effects

Inactive Publication Date: 2006-04-26
吉林威威药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] None of the above-mentioned patents involves the combination of Folium Folium Folium and Houttuynia cordata alone for extraction and preparation of new drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Take 6 kg of Houttuynia cordata, wash and chop, add 60 kg of water, heat and distill for extraction, collect the initial distillation liquid, and re-distill and extract the initial distillation liquid once to obtain volatile oil, and the residue is for later use;

[0040]Mix 10kg of roadside greens and Houttuynia cordata residue after extracting the volatile oil of Houttuynia cordata, add 8 times the weight of the mixture to decoct for 3 hours, pour out the decoction, add the same 8 times the weight of water and decoct for 2 hours, pour Go out decoction liquid and combine, filter, and filtrate is concentrated to 5.5kg, adds 2.75g clarifying agent B (produced by Tianjin Zhengtiancheng Clarification Technology Co., Ltd.) in concentrated liquid, heats to 80 ℃, after standing for 2 hours, add to concentrated liquid Add 1.38g clarifier A (produced by Tianjin Zhengtiancheng Clarification Technology Co., Ltd.), let it stand for 4 hours, use a high-speed tube centrifuge to centr...

Embodiment 2

[0043] Take 3 kg of Houttuynia cordata, wash and chop, add 36 kg of water, heat and distill and extract, collect the initial distillation liquid, and re-distill and extract the initial distillation liquid once to obtain volatile oil, and the residue is for later use;

[0044] Mix 9 kg of roadside greens and the Houttuynia cordata residue after extracting the volatile oil of Houttuynia cordata, add 8 times the weight of the mixture to decoct for 2 hours, pour out the decoction, add the same 8 times the weight of water and decoct for 1 hour, pour Take out the decoction and combine, filter, concentrate the filtrate to 4kg, add 0.06% of its weight clarifier B to the concentrated solution, heat to 70 ° C, after standing for 2 hours, add 0.03% of its weight of clarifier B to the concentrated solution A. After standing for 4 hours, use a high-speed tube centrifuge to centrifuge, add ethanol to the supernatant until the alcohol content reaches 70%, keep it at 2°C for 10 hours, recover ...

Embodiment 3

[0047] Take 5 kg of Houttuynia cordata, wash and chop, add 50 kg of water, heat and distill and extract, collect the initial distillation liquid, and re-distill and extract the initial distillation liquid once to obtain volatile oil, and the residue is for later use;

[0048] Mix 5kg of roadside greens and Houttuynia cordata residue after extracting the volatile oil of Houttuynia cordata, add 6 times the weight of the mixture and decoct for 3 hours, pour out the decoction, filter, concentrate the filtrate to 3.3kg, add to the concentrate 0.04% by weight of clarifier B, heated to 90°C, and after standing for 2 hours, add 0.02% by weight of clarifier A to the concentrated solution, and after standing for 4 hours, use a high-speed tube centrifuge to centrifuge the supernatant Add ethanol until the alcohol content reaches 72%, keep at 8°C for 12 hours, recover the ethanol to obtain a recovered solution, add 12 times the amount of water for injection to the recovered solution, keep ...

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Abstract

The present invention relates to a novel pharmaceutical composition, specifically a novel pharmaceutical composition prepared by combining Folium Folium Folium and Houttuynia cordata and extracting active ingredients. The raw material medicine includes raw medicinal materials Folium Folium and Houttuynia cordata, wherein the raw medicinal material Houttuynia cordata is 1-1000 parts by weight, and the weight of Folium folium is 0.1-10 times that of Houttuynia cordata. When preparing the composition, the volatile oil in Houttuynia cordata is extracted first, the residue is mixed with Daqingye and then decocted, the concentrated solution is treated with a clarifying agent, and the Daqingye and Houttuynia are obtained through alcohol precipitation, water precipitation and filtration. The residue extract solution is mixed with the volatile oil and the extract solution, and various dosage forms of the pharmaceutical composition are obtained through post-processing. The pharmaceutical composition can be used for treating viral influenza, upper respiratory tract infection, mumps, pneumonia and other diseases.

Description

technical field [0001] The present invention relates to a kind of pharmaceutical composition, its preparation method and application thereof, specifically, to a kind of new pharmaceutical composition prepared by extracting effective components from the combination of Folium Folium Folium and Houttuynia cordata, and its preparation The method and its application in the preparation of medicines for treating viral influenza, upper respiratory tract infection, mumps, pneumonia and other diseases. Background technique [0002] Chinese herbal medicine Daqingye has the effect of clearing heat and detoxifying, cooling blood and stopping bleeding, which are contained in "Compendium of Materia Medica" and "Plant Names and Facts". Chinese medicine believes that Folium Folium is cold in nature and bitter in taste, can clear away heat, detoxify, cool blood and stop bleeding. Modern pharmacological research shows that: [0003] (1) Folium Folium has antiviral effect; Folium Folium of di...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/855A61K9/00A61P31/12A61P11/00
Inventor 郭志华
Owner 吉林威威药业股份有限公司
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