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Chinese medicinal composition for treating intestine irritable syndrome and its preparing method

A technology for irritable bowel syndrome and composition, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, can solve problems such as side effects, and achieve high bioavailability, easy portability, and reasonable formulation. Effect

Active Publication Date: 2006-06-07
CONSUN PHARML NEI MENG GU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the chemical drugs currently on the market have curative effects, they are often accompanied by certain side effects, which makes psychotherapy occupy a very important position in the treatment of this disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0109] Embodiment 1. The preparation of the traditional Chinese medicine composition for treating irritable bowel syndrome and its preparation of the present invention.

[0110] Expand the amount of medicine according to the following prescription in equal proportions and take the medicine for later use: 20 grams of Atractylodes macrocephala, 14 grams of white peony, 10 grams of tangerine peel, and 10 grams of Fangfeng; add 9 times the amount of water for Atractylodes macrocephala, tangerine peel, and Fangfeng, soak for 1.5 hours, and extract for 4 hours Volatile oil, collect the volatile oil, filter the medicinal liquid, and set aside; add 80% ethanol to the obtained medicinal residue and white peony root, soak for 1 hour, extract twice, each time for 1 hour, add 9 times the amount for the first time, and add 6 times for the second time The above two filtrates were combined and concentrated, concentrated to a relative density of 1.08 (80°C), filtered through 80-160 mesh, centr...

Embodiment 2

[0117] Expand the amount of medicine according to the following prescription in equal proportions and take the medicine for later use: 25 grams of Atractylodes macrocephala, 20 grams of white peony, 15 grams of tangerine peel, and 15 grams of Fangfeng; add 9 times the amount of water for Atractylodes macrocephala, tangerine peel, and Fangfeng, soak for 1 hour, and extract for 4 hours Volatile oil, collect the volatile oil, filter the medicinal liquid, and set aside; add 80% ethanol to the obtained medicinal residue and white peony root, soak for 1 hour, extract twice, each time for 1 hour, add 9 times the amount for the first time, and add 6 times for the second time The above two filtrates were combined and filtered, the filtrate was concentrated under reduced pressure to a relative density of 1.35 (80°C), alcohol precipitation twice, the ethanol concentration was adjusted to 80%, and the supernatant was taken Concentrate to a relative density of 1.35 (80°C); take the above ex...

Embodiment 3

[0119] Embodiment 3. is substantially the same as embodiment 1, but the prescription ratio is:

[0120] 15 grams of Atractylodes macrocephala, 8 grams of Radix Paeoniae Alba, 5 grams of tangerine peel, 5 grams of Fangfeng, and the rest are the same as in Example 1.

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Abstract

The traditional Chinese medicine composition for treating irritable bowel syndrome includes: 15-30 grams of Atractylodes macrocephala, 8-25 grams of white peony root, 5-20 grams of tangerine peel, and 5-20 grams of Fangfeng. Or: volatile oil components of Atractylodes macrocephala, tangerine peel and Fangfeng; ethanol extraction components of Atractylodes macrocephala, tangerine peel, Fangfeng, and white peony root; appropriate amount of vegetable oil. Prescriptions can be directly used clinically, or after addition and subtraction. Its preparation method: take Atractylodes macrocephala, tangerine peel and Fangfeng, add water to soak, extract and collect volatile oil, and filter the medicinal solution; add ethanol to the medicinal residue and white peony root, soak, extract, and filter; the above two filtered solutions are combined and concentrated to obtain an extract , add volatile oil and vegetable oil, mix well, that is. Soft capsules and soft capsule dosage forms made by soft capsule molding process have the advantages of rapid disintegration, high bioavailability, good stability, beautiful appearance, easy to carry, easy to take, etc. Hard capsules, granules, Common dosage forms such as tablets, oral liquids, and suppositories also have the above advantages.

Description

technical field [0001] The invention relates to a prescription composition, a preparation method, a molding process and a preparation of a traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating irritable bowel syndrome (IBS) and a preparation method thereof. Background technique [0002] Irritable bowel syndrome (IBS) is a common clinical functional intestinal disease, accounting for about 30% of gastrointestinal diseases, especially in young and middle-aged people. Questionnaire studies have shown that the prevalence of irritable bowel syndrome (IBS) in adults is 10%-22%, and it is slightly more common in women. Its main clinical manifestations are abdominal pain, diarrhea, constipation and other digestive system symptoms. The etiology is gastrointestinal dysfunction. [0003] Factors related to irritable bowel syndrome are: ①Dietary factors: A high-fiber diet can reduce the transit time of food in the intestinal tract and i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61K131/00A61K9/48A61P1/00A61P25/06
Inventor 储益平时贞平王殿广朱春霞
Owner CONSUN PHARML NEI MENG GU
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