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Improved method for preparing 'Zhenqi Fuzheng' medicine

The technology of Zhenqi Fuzheng and medicinal powder is applied in the field of preparation and improvement of Zhenqi Fuzheng medicine, which can solve the problem that it cannot be used for preparing injections, and achieves the effects of reducing the quantity, improving the stability and increasing the content.

Inactive Publication Date: 2006-10-18
甘肃扶正药业科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] It is precisely because of the presence of impurities in the medicine prepared by the prior art that it cannot be used for the preparation of injections

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0019] The present invention provides the embodiment that several different formulations are produced below:

[0020] 1. Powder preparation

[0021] Take the prescription amount of Ligustrum lucidum and add 30% to 95% ethanol to reflux and extract several times, add 3 to 12 times the amount of ethanol each time, filter the reflux liquid, combine the filtrate, recover the ethanol and concentrate under reduced pressure to a relative density of 1.05 to 1.10 ( 50°C), add appropriate amount of water under stirring, let it stand, filter, dry the sediment, and set aside; add water to decoct several times of Ligustrum lucidum dregs, add 3 to 12 times the amount of water each time, and filter the decoction After drying, combine the filtrates, concentrate under reduced pressure to a clear paste with a relative density of 1.10-1.15 (50°C), add ethanol to make the alcohol content reach 30%-95%, stir well, stand and filter, and dry the precipitate for later use. Take the prescribed amount...

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PUM

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Abstract

The invention relates to the improvement of the preparation method of the existing drug "Zhenqi Fuzheng". The present invention extracts Astragalus membranaceus and Ligustrum lucidum with water and alcohol respectively, and the water extract is precipitated with alcohol to precipitate polysaccharides, so that the active ingredients such as polysaccharides in medicinal materials and zidonolic acid in Ligustrum lucidum can be fully extracted. It is proposed that the extract of Astragalus membranaceus is treated with macroporous adsorption resin, which can effectively remove the mucus, gums and other ineffective components in the water extract of Astragalus membranaceus, and enrich the effective components to a certain extent. And then reach the purpose of reducing the amount of clinical drug use, and bring the possibility for the production of injections.

Description

technical field [0001] The invention relates to the improvement of the preparation method of the existing drug "Zhenqi Fuzheng". Background technique [0002] Zhenqi Fuzheng medicine is produced by combining plant medicine Astragalus and Ligustrum lucidum in a ratio of nearly 2:1 (weight ratio), which is used to improve immunity and treat leukopenia caused by radiotherapy or chemotherapy. In the prior art, the production process of Zhenqi strengthening medicine is to crush Astragalus membranaceus and Ligustrum lucidum into coarse powder, then decoct with water, then dry the water extract to obtain medicinal powder, and then pack the medicinal powder into capsules to form a commercial drug. Ineffective ingredients such as mucus and gum contained in the medicinal material itself all enter in the extractum when produced with the prior art, but the active ingredients of the medicine are lower. Because contained active ingredient is less, in order to reach the amount of effectiv...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61K36/185A61K9/48A61K9/20A61K9/08A61K9/10A61P37/04
Inventor 席倬霞李建华高岩
Owner 甘肃扶正药业科技股份有限公司