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Granule of Jingangteng for treating inflammatory gynecopathy and its preparation method

A technology for gynecological inflammation and granules is applied in the field of traditional Chinese medicine preparations for the treatment of gynecological inflammatory diseases and the field of preparation thereof, which can solve the problems such as the unreported medicines of Radix vulgaris, inconspicuous pharmacological effects, inconvenient transportation and carrying, etc. Easy to transport, take and carry, long-lasting effect

Inactive Publication Date: 2007-02-07
陕西海天制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the syrup also has many deficiencies in actual use, such as inconspicuous pharmacological effects, large doses, difficult preservation, inconvenient transportation, etc.
Due to the lack of research on the chemical composition, pharmacological effects and new dosage forms of King Kongteng in the past, and the limitation of the use route and some other factors, the development of other dosage forms of King Kongteng medicine has not been reported so far.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Take 3000g of King Kong vine, add water and decoct three times, 1 hour each time, combine the decoction, filter, concentrate the filtrate to a relative density of 1.05, add ethanol to make the ethanol content in the solution 40%, let it stand for 24 hours, filter , the filtrate recovers ethanol, concentrates to a clear paste with a relative density of about 1.20 (60°C thermal measurement); take 1 part of clear paste, 4 parts of sucrose, and 1 part of dextrin, mix well, make granules, dry, pack, and prepare Obtain the sugar-containing soluble granule of the present invention.

Embodiment 2

[0020] Get 3000g of King Kong vine, add water and decoct 2 times, each time for 1.5 hours, combine the decoction, filter, the filtrate is concentrated to a relative density of 1.10, add ethanol, make the ethanol content in the solution be 45%, let stand for 36 hours, filter The ethanol is recovered from the filtrate, concentrated to a clear paste with a relative density of about 1.22 (60°C thermal measurement); take 1 part of the clear paste, 5 parts of dextrin, and 0.035 part of stevioside, mix well, make granules and dry them, and pack them separately, namely The sugar-free soluble granules of the present invention are prepared.

Embodiment 3

[0022] (1) Get 4320g of King Kong vine, take out 3800g of it and add 6 times the amount of 70% ethanol to soak for 15 hours, heat and reflux to extract 2 times, each 2.5 hours, combine the extracts, filter, and the filtrate is concentrated under reduced pressure to a relative density of 1.18 (60°C) thick paste.

[0023] (2) Take the above thick paste, dry it under vacuum at 50-60°C, and grind it into fine powder.

[0024] (3) Take the remaining amount of the vine of the above-mentioned step (1), grind it into a fine powder, mix it with the fine powder obtained in the above-mentioned step (2), granulate, dry, granulate, and pack to obtain the sugar-free Suspension granules.

[0025] The present invention provides a natural medicine for treating gynecological inflammatory diseases. In order to prove its therapeutic effect and safety, the inventor used the granules prepared by the method provided in the above-mentioned Example 1 to carry out toxicological and pharmacodynamic tes...

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PUM

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Abstract

A Chinese medicine in the form of particles for treating gynecologic inflammation, such as annexitis, is prepared from bock greenbrier rhizome. Its preparing process is also disclosed. Its advantage is sure curative effect.

Description

Technical field [0001] The invention belongs to the technical field of preparation of medicines, and relates to a Chinese patent medicine preparation for treating gynecological inflammatory diseases and a preparation method thereof. Background technique [0002] Gynecological inflammatory diseases such as adnexitis and adnexal inflammatory mass are common clinical diseases and frequently-occurring diseases. At present, there are many drugs used to prevent and treat gynecological inflammatory diseases in this field, especially some traditional Chinese medicine preparations in clinical practice. In practice, quite unique curative effect advantages have also been formed. However, due to the high incidence of gynecological inflammatory diseases and complicated pathological mechanisms, some existing pharmaceutical preparations still cannot fully meet the needs of clinical and market needs, and still need to be developed by scientific research institutions and experts. The personn...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K9/16A61K9/10A61P15/00A61P29/00A61K125/00
Inventor 王春王宇张国莹王辉
Owner 陕西海天制药有限公司