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Application of atractylodes rhizome oil in preparing medicine for osteoporosis

A technology for osteoporosis and atractylodes oil, which can be used in drug combinations, bone diseases, pharmaceutical formulations, etc., and can solve problems such as ineffective curative effects

Inactive Publication Date: 2003-09-10
SHANDONG ACAD OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In terms of traditional Chinese medicine treatment, mainly Chinese medicines for nourishing the kidney and calcium are used to treat osteoporosis, and they are only limited to adjuvant treatment, and the curative effect is not very significant

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0137] Get the herb oil 100g that embodiment 1 extracts, mix by Atractylodes oil, salad oil 1: 1 (weight) stand-by.

[0138] According to the ratio of gelatin: glycerin: water (2:1:2) (weight), take gelatin, add appropriate amount of water to make it swell, heat to 70°C, add glycerin and remaining water, heat, stir to melt, let stand to remove foam, Filter out impurities, add 0.16% (weight) of hydroxybenzoic acid ester, 0.04% (weight) of propyl hydroxyformate, mix, and the glue viscosity remains 40mpas -1 Around, the temperature of the glue solution is kept at about 60°C, the room temperature is 21-24°C, and the relative temperature is 40-45%. The weight is 0.2g / grain, and the weight of the volatile oil contained therein is 0.1g / grain. Cool and shape for more than 4 hours, wash the pills with ethanol, dry at 30-35°C for 12-15 hours, put the pills in a sugar-coated pan, polish them with paraffin wax, and bottle them to obtain 1000 finished products in total.

Embodiment 3

[0140] Take 25 g of the volatile oil of Example 1 and use 250 g of β-cyclodextrin (weight ratio 1:10) for inclusion, crush 250 g of oysters into fine powder, sieve, and mix evenly with Atractylodes atractylodes oil β-cyclodextrin inclusion and its auxiliary materials , Tablets, 0.5g per tablet, and a total of 1000 tablets were prepared.

[0141] Usage and dosage: Take orally, 4 tablets at a time, 2 times a day. 4. Embodiment 4

Embodiment 4

[0142] Take 25 g of the volatile oil of Example 1 and use 250 g of β-cyclodextrin (weight ratio 1:10) for inclusion, crush 250 g of oysters into fine powder, sieve, and mix evenly with Atractylodes atractylodes oil β-cyclodextrin inclusion and its auxiliary materials , packed in capsules, each capsule 0.5g, a total of 1000 capsules were prepared. Usage and dosage: Take orally, 4 capsules each time, 2 times a day. 5. Embodiment 5

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PUM

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Abstract

The present invention relates to the application of atractylodes rhizome oil in preparing medicine for osteoporosis. Atractylodes rhizome oil is extracted from atractylodes rhizome and is volatile. The medicine is prepared in tablet, capsule, granule or other forms, preferably soft capsule owing to the volatility of atractylodes rhizome oil. In order to obtain ever higher treating effect and increase the absorption of calcium, it is preferably to add superfine crushed oyster powder into the preparation. The present medicine is safe, efficient, low-toxicity and stable osteoporosis treating medicine.

Description

[0001] (1) The technical fields mentioned [0002] The invention relates to the application of herb oil in the preparation of medicine for treating osteoporosis. (2) Background technology [0003] Osteoporosis (OPS for short) is a common geriatric disease characterized by low bone mass and degeneration of the fibrous structure of bone tissue. There is no proven treatment. The main manifestations of this disease are fractures and invasion of the spine, causing complications such as low back pain and shortened body length. It is a serious disabling disease. [0004] With the improvement of people's living standards, people's life expectancy is getting longer and longer, and the trend of population aging is becoming more and more serious. As a common and frequently-occurring disease of the elderly, the incidence of osteoporosis will further increase. At present, there is no ideal therapy and medicine that can fundamentally cure osteoporosis. In terms of traditional Chinese med...

Claims

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Application Information

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IPC IPC(8): A61P19/10
Inventor 阎雪生李贵海薛一涛张希林姚乾元
Owner SHANDONG ACAD OF CHINESE MEDICINE
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