Vero cell fick-borne encephalitis inactivated vaccine

Abstract

An deactivated vero cell vaccine for forest encephalitis virus is composed of the deactivated forest encephalitis virus and vaccine adjuvant. Its preparing process includes inoculating the forest encephalitis virus to vero cells, culturing to obtain the culturing liquid, purifying, and preparing said vaccine. Its advantages are high purity, high immunizing effect and high safety.

Description

Vero Cell Forest Encephalitis Inactivated Vaccine technical field The invention belongs to the field of biopharmaceuticals, and in particular relates to an inactivated Vero cell forest encephalitis vaccine and a preparation method thereof, in particular to a method for industrially preparing an inactivated Vero cell forest encephalitis vaccine and the vaccine prepared by the method. Background technique Forest encephalitis is caused by forest encephalitis virus. Ticks are the main source of infection. It is a natural foci acute infectious disease mainly invading the central nervous system. The case fatality rate is 20-30%. Healthy viral infectious disease. Vaccines for the prevention of forest encephalitis. Successively experienced the preparation of forest encephalitis inactivated vaccines with mouse brain, chicken embryo, hamster kidney and other matrices. At present, the inactivated vaccine of forest encephalitis of hamster kidney cells is used in my country; the inac...

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Problems solved by technology

Vero cell poliomyelitis inactivated vaccine, polio vaccine, Vero cell rabies vaccine have been cultivated and developed in France successively and approved for production, and there are reports on the application of Vero cells to prepare vaccines, but about the application of Vero cells to prepare forest encephalitis vaccine research has not yet been reported

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