Swine growth promoters and method of promoting swine growth

A growth promoter and growth-promoting technology, applied in pharmaceutical formulas, animal feeds, additional food elements, etc., can solve problems such as spoilage of feed taste, long time, and poor absorption of iron components.

Inactive Publication Date: 2004-10-20
COSMO ALA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, although the administration of iron preparations has some effects in improving physiological anemia and preventing diseases, it is not effective in promoting growth
Furthermore, the problem with oral administration of the iron component is that the intestinal absorption of the iron component is poor and that the iron component spoils the taste of the feed, while on the other hand, the problem with the injection is that it requires stress on the pig, compared to oral administration, which requires spend more time
[0004] 5-aminolevulinic acid is known to have herbicidal action (JP-A-61-502814 and JP-A-4-9360), insecticidal action (JP-A-2-138201), sensitization to photodynamic therapy of cancer effect, plant growth-promoting effect (Japanese Patent No. 2,613,136), etc., but the possibility of promoting pig growth is unknown

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Using large Yorkshire piglets born between September and October 2000, on the third day after birth, 50 mg of 5-aminolevulinic acid hydrochloride per 1 kg of body weight was dissolved in 2 ml of distilled water, and subjected to Orally administered to the "ALA area", conventional iron-dextran (manufactured by Takeda Pharmaceutical Co., Ltd.) was administered to the "iron area" by intramuscular injection, and both treatments were performed together in the "ALA+iron area". Furthermore, in the "untreated area", it was not administered.

[0033] After that, the usual management was carried out, and feeding was started on the 14th day after birth, and the body weight was measured and blood samples were collected on the 21st day after birth, so as to be checked by the usual method. Similarly, the body weight was measured after about 6 months, and the number of days to reach the weight standard of 110 kg for the slaughter (that is, the number of days required to reach 110 kg) ...

Embodiment 2

[0052] Piglets born between October and November 2000 were used and fed on day 14 after birth. Its growth status was observed in the following three areas: the area fed with common feed; the area where 5-aminolevulinic acid hydrochloride was added to ordinary feed in the form of 10 mg per 1 kg of feed (ALA area); Add 10 mg ferric ammonium citrate area (ALA+iron area) to the above feed to obtain the required days to reach 110 kg. The results are shown in Table 3.

[0053] In this embodiment, 10 animals per district were used for testing, and the average value was calculated.

[0054] Days required to reach 110kg

[0055] As evident from Table 3, the growth of piglets was significantly enhanced in both the ALA zone and the ALA+iron zone, showing effective results. In this respect, in Example 2 no pigs were found to leave the test due to illness.

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PUM

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Abstract

A pig growth enhancer, which comprises, as an active ingredient, at least one compound selected from 5-aminolevulinic acid, a derivative thereof and a salt thereof, and a method for enhancing pig growth, which comprises administering the growth enhancer to a pig.

Description

technical field [0001] The present invention relates to a porcine growth promoting agent and a pig growth promoting method using the growth promoting agent. Background technique [0002] Pigs are useful livestock raised to provide meat for consumption, are fast growing and have a high conversion rate of grain to meat. However, they exhibit symptoms such as physiological anemia while growing rapidly, especially in the early stage of their growth, and often lead to growth inhibition and disease onset. As a countermeasure, drugs (iron preparations) and various nutritional agents can be administered, but the effect is limited. In particular, in the early growth stage, in order to improve the symptoms of physiological anemia, iron-dextran injections and oral administration of iron sulfate and iron fumarate can be used. [0003] However, although the administration of iron preparations has some effects in improving physiological anemia and preventing diseases, it is not effectiv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/197A61K31/295A61K33/26A61P3/00A61P43/00
CPCA61K33/26A23K1/18A61K31/295A61K31/197A23K1/1634A23K1/1893A23K1/1758A23K20/142A23K20/30A23K50/00A23K50/60A61P3/00A61P43/00A61P7/06Y02P60/87A61K2300/00
Inventor 押田敏雄田中彻
Owner COSMO ALA CO LTD
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