Propolis dripping pills for treating toothache and its preparation method

A technology of Tong Dropping Pills and Propolis, applied in the field of clearing heat and detoxifying, can solve the problems of long dissolution time, inconvenience to carry out, short shelf life, etc., to avoid gastrointestinal irritation, improve bioavailability, and accelerate dissolution and absorption Effect

Inactive Publication Date: 2005-07-06
北京博智绿洲医药科技有限公司
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Problems solved by technology

[0012] Propolis toothache tincture is a liquid oral preparation. Due to the preparation technology and other reasons, the tincture has the characteristics of low drug content, large dosage, inaccurate dosage, inconvenient use, and inconvenient to carry out. It is easy to produce Precipitation, its shelf life is relatively short, etc.
[0013] In addition, other conventional traditional Chinese medicine solid oral dosage forms, such as tablets, capsules, granules, etc., have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic first-pass effect and low bioavailability after taking them. , thus affecting t

Method used

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Examples

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Embodiment Construction

[0039] The preparation method of propolis Yatong dripping pills of the present invention will be further described with several groups of specific examples.

[0040] Group 1: Tests with a single matrix

[0041] 1. Weigh a certain amount of traditional Chinese medicine raw materials according to the ratio given in [Preparation Method] 1, and then follow the section [Appendix: Preparation Method of Propolis Extract] to first prepare extract extract or dry powder containing propolis pure Chinese medicine active ingredients and Metronidazole is combined into a mixed drug extract for later use; clove oil 45ml is for later use;

[0042] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、9300、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0043]3. Proportion—in g or kg, in parts by weight, drug extract: matrix = 1...

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Abstract

The invention discloses a bee glue drop pill for treating dentalgia, which is a medicinal composition with the functions of relieving pain, haemostasis and the auxiliary treatment for periodontitis. The pharmaceutical composition is prepared from bee glue as the raw material through the conventional drop pill preparing process.

Description

technical field [0001] The invention relates to a medicinal composition for clearing heat and detoxification, reducing swelling and relieving sore throat; it is used for sore throat, single and double milk moth, Dansha furunculosis, carbuncle furuncle and swollen toxin, especially relates to propolis toothache formulated with traditional Chinese medicine Tincture as the basis, a kind of pharmaceutical composition oral drop pill preparation that is reformed by dosage form. Background technique [0002] The propolis toothache tincture prepared according to the formula and extraction process given in the national drug standard WS-11255 (ZD-1255)-2002 is a tincture preparation with pain relief, hemostasis, and adjuvant treatment for periodontal inflammation. , has been clinically verified for many years, with stable quality and definite curative effect. It is a commonly used pharmaceutical preparation for clinical and family use to treat the above diseases. There are currently ...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K35/644A61P1/02
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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