Drop pills for treating throat diseases and preparation method thereof

A technology for sore throat and function, applied in the field of Liuling Dropping Pills for treating throat diseases and the field of preparation thereof, can solve the problems of inaccurate dosage, low dissolution rate, increased drug cost, etc., and achieves improved bioavailability, solubility and The effect of accelerated absorption and increased total surface area

Inactive Publication Date: 2005-07-06
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] Liuling pills are solid oral preparations. The oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have long dissolution time, low dissolution rate, poor absorption, hepatic first-pass effect and low bioavailability after taking. And other problems, which affect the efficacy of the drug, but also directly affect the therapeutic effect
Due to the preparation technology and other reasons, the pellets have the characteristics of low drug content, large dosage, inaccurate dosage, and inconvenient administration.
In addition, other conventional traditional Chinese medicine solid oral dosage forms, such as tablets, capsules, granules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0037] Now with several groups of specific examples, the preparation method of Liuling dripping pills of the present invention will be further described.

[0038] Group 1: Tests with a single matrix

[0039] 1. According to [preparation method] 1, first prepare the dry medicine powder containing 6 kinds of traditional Chinese medicines such as artificial bezoar, pearl, musk, borneol, realgar, toad venom, etc.;

[0040] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、9300、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0041] 3. Proportion—take g or kg as the unit, in parts by weight, drug dry powder: matrix = 1:1~1:9;

[0042] 4. Then prepare according to the process of [Preparation Method] 4 to 7, that is, Liuling dripping pills of various specifications can be prepared.

[0043] [test results]

[0044...

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PUM

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Abstract

The invention relates to a medicinal oral preparation for treating throat pain, furuncle and carbuncle, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has heat-clearing and toxic substances removing, detumescence and relieving sore throat; It is used for treating symptoms such as sore throat, single and double breast moth, Dan Sha furunculosis, carbuncle furuncle and swollen toxin, especially relates to the traditional Chinese medicine formula six Lingwan is a pharmaceutical composition oral drop pill preparation reformed through formulation. Background technique [0002] According to the drug standard of the Ministry of Health, the traditional Chinese medicine preparation WS 3 -Liuling Pill prepared according to the prescription and method given in B-3773-98, has the functions of clearing away heat and detoxification, reducing swelling and relieving sore throat; Symptomatic pellet preparations for the treatment of swelling and poisoning have been clinically verified for many years, with stable quality and definite curative effect....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P11/04
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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