Carefree drop pills in use for soothing the liver and invigorating the spleen as well as enriching the blood and regulating menstruation, and preparing method

A dripping pill and Xiaoyao technology, which is applied to Xiaoyao dripping pills for soothing the liver and strengthening the spleen, nourishing blood and regulating menstruation and its preparation field, can solve the problems of inaccurate dosage, short shelf life, large dust pollution, etc., and achieve the improvement of biological Utilization, faster dissolution and absorption, no dust pollution effect

Inactive Publication Date: 2005-08-31
BEIJING BORAN PHARM CO LTD +1
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  • Abstract
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  • Application Information

AI Technical Summary

Problems solved by technology

[0022] Due to preparation technology and other reasons, oral preparations of most drugs, especially solid oral preparations of traditional Chinese medicine, have long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. problems, thus affecting the efficacy of the drug, and directly affecting the therapeutic effect
However, mixtures and honeyed pills also have low drug content, large doses, inaccurate doses, and inconvenient taking.
At the same time, the types of preparations with high sugar content are not conducive to the consumption of diabetics.
Water pills are often prone to mildew due to inconvenient storage,

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0050] The preparation method of Xiaoyao Dropping Pills of the present invention will be further described with several groups of specific examples.

[0051] Group 1: Tests with a single matrix

[0052] 1. According to Appendix 1 or Appendix 2, first prepare the extract extract or dry powder containing pure active ingredients of traditional Chinese medicine for later use;

[0053] 2. Substrate: polyethylene glycol (1000～20000) , Polyoxyl 40 Stearate, β-Cyclodextrin, Poloxamer, Sodium Carboxymethyl Starch, Sodium Lauryl Sulfate, Stearic Acid, Sodium Stearate, Glycerin Gelatin, Insect Wax, Insect Pharmaceutically acceptable carriers such as gelatin:

[0054] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:0.5~1:6;

[0055] 4. Then prepare according to the process of [Preparation Method] 4-7, and various specifications of Xiaoyao Dropping Pills can be prepared.

[0056] [test results]

[0057] Experiment 1: In order to observe the difference in q...

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PUM

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Abstract

A Chinese medicine 'Xiaoyao dripping pill' for treating the disorder of liver Qi, hypochondriac pain, dizziness, anorexia, menoxenia, etc, and its preparing process are disclosed.

Description

technical field [0001] The invention relates to a pharmaceutical composition which has the functions of soothing the liver and invigorating the spleen, nourishing blood and regulating menstruation, and is used for treating symptoms such as insufficient liver qi, chest pain, dizziness, loss of appetite, and irregular menstruation. A medicine composition oral drop pill preparation prepared based on the extraction process of Xiaoyao Granules and Xiaoyao Mixture. Background technique [0002] National Drug Standard WS 3 - Xiaoyao Granules published in B-2968-2002 and Ministry of Drugs Standard WS 3 - The Xiaoyao Mixture published in B-2221-96 has the functions of soothing the liver and strengthening the spleen, nourishing the blood and regulating the menstruation, etc. It is used for the treatment of symptoms such as liver qi deficiency, chest rib pain, dizziness, loss of appetite, and irregular menstruation. Pure Chinese medicine preparations have been clinically verified wit...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P1/14A61P15/00
Inventor 刘志勤曲韵智彭晓云黄成武
Owner BEIJING BORAN PHARM CO LTD
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