Method for preparing oligonucleotide chip in use for DNA surface computer in heterozygosis with computer

An oligonucleotide and surface computing technology, which is applied in the field of preparation of oligonucleotide chips for DNA surface computing, can solve the problems of increasing variable operation, inability to use, errors, etc., and achieves simple operation process and reduced false positive rate. Effect
CN1661101AInactive Publication Date: 2005-08-31SHANGHAI JIAO TONG UNIV
0 Cites 8 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHANGHAI JIAO TONG UNIV
Publication Date
2005-08-31
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

A process for preparing oligonucleotide chip used in DNA surface calculation to solve the NP question is disclosed, which features that the coding and arranging of the oligonucleotide sequenes on DNA surface calculation chip are in such manner that the data in data pool is converted to the binary form, the data pool is converted to an array, and each data in the array is mapped to an oligonucleotide sequence, that is, a point on the chip.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a preparation method used in the technical field of DNA chips, in particular to a preparation method of an oligonucleotide chip for computing a DNA surface hybridized with a computer. Background technique

[0002] In 1994, Adleman (Science, 1994, 266: 1021-1024) used DNA sequence as the information carrier for the first time, and used molecular biology test technology to solve an NP-complete problem (Hamilton path problem with seven vertices) in a test tube, and pointed out that DNA molecules The calculation has the characteristics of high information degree and high parallelism, so that it can solve difficult problems such as NP-complete problems in linear time. If these NP-complete problems are solved by Turing machines, the time required is exponentially increasing. After Adleman, many scholars proposed a variety of DNA computing models for different NP problems, involving SAT problems, maximum clique problems, maximum inde...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More