Adipose transplantation material containing highly concentrated adipose-derived stem cells and extracellular matrix, and pure physical preparation method and application thereof
A fat-derived, highly concentrated technology, applied in the field of fat transplantation and stem cell therapy, can solve the problems of high cost, complicated separation process, limited capacity, etc., and achieve the effect of low cost, rich source, and no rejection.
Active Publication Date: 2016-12-07
鲁峰
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The invention discloses an adipose transplantation material containing highly concentrated adipose-derived stem cells and an extracellular matrix (ECM), and a pure physical preparation method and an application thereof; with application of a fluid vortex principle, most of mature adipocytes in an adipose tissue are broken; at the same time, with application of a flocculation sedimentation technology, oil droplets generated from breaking the adipocytes are gathered and removed. A series of mechanical processing processes are adopted, the pure physical means is adopted, and no any exogenous substances are added. The multiple physical methods are used for removing the mature adipocytes and grease affecting the tissue retention rate after transplantation. In a prepared SVF-gel, the adipose-derived stem cells and endothelial progenitor cells are highly concentrated; the concentrated stromal vascular fraction cells (SVFs) still adhere on the ECM, the number of stem cells fix-planted in local after transplantation is far greater than the ordinary adipose transplantation number; as a stem cell therapy method, the adipose transplantation material has better long-term curative effect.
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Fat graftingOil droplet +15
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