Process for preparing high-immune serum for main epidemic disease of dog and formulation thereof

Abstract

The invention provides a process for preparing high-immune serum for main epidemic disease of dog and formulation, which comprises subjecting one or several pathogens causing serious diseases of canine animals to culture and propagation of primary or passage cell or bacteria culture media of dogs, monkeys and cats, charging adjuvant to obtain immunogens, immuning the canine animals and separating serum, eradicating virus, finally making single or combined serum or antibody preparation.

Description

Technical field:

[0001] The present invention relates to the preparation process of hyperimmune serum against important canine diseases of canines, and in particular provides a preparation process and preparation of hyperimmune serum of canines against important canine diseases, which is used for emergency prevention of corresponding important diseases of canines and treatment, belonging to the field of biological product development. Background technique:

[0002] Along with dog, raccoon dog, fox and other canine fur animal breeding industry develops continuously in our country, the number of fur animal breeding reaches several million every year. However, many important diseases of canine animals such as canine distemper, canine parvovirus disease, canine infectious hepatitis (fox encephalitis), canine infectious laryngotracheitis, canine influenza, canine parainfluenza, canine coronavirus disease, canine leptovirus The continuous occurrence of epidemic diseases such as s...