Emulsive water-soluble concentrates

An emulsion-like, water-soluble technology, which can be used in emulsion delivery, pharmaceutical formulations, medical preparations with inactive ingredients, etc., and can solve problems such as cell toxicity.

Active Publication Date: 2006-02-22
LIPOID GMBH (DE)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these solubilizers have serious deficiencies
[0009] - highly volatile alcohols - VOC - (ethanol, isopropanol) are toxic to cells, and - are undesirable in many formulations due to atmospheric protection concerns

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] 5 g of phospholipids obtained from soybeans containing phospholipids (PC) 70% were dispersed by stirring in 75 g of 86% glycerol. Add 20 grams of vitamin E acetate to disperse with continuous stirring. Homogenize the initially dispersed inhomogeneous mixture with a high-pressure homogenizer. A clear emulsion with high viscosity is obtained.

Embodiment 2

[0030] 5 grams of phospholipids obtained in soybeans containing phospholipids (PC) 70% were stirred and dispersed in 75 grams of 70% fructose solution. After adding 20 g of medium-chain triglycerides, the mixture was homogenized under high pressure to obtain a transparent emulsion with a honey-like viscosity.

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PUM

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Abstract

The invention relates to the solubilization of lipophilic substances, preferably from the group of lipids, steroids, terpenes, and polar lipids, by means of a lecithin / polyol matrix or a lecithin / carbohydrate matrix so as to obtain water-soluble, emulsive, transparent concentrates which are used in cosmetic, dietary, and pharmaceutical products.

Description

technical field [0001] The present invention relates to an emulsion-like transparent to translucent water-soluble concentrate according to the features of claim 1 and its use in cosmetics, medicine or food. Background technique [0002] Lipophilic or lipid substances often have to be converted into problem-free application forms in the pharmaceutical, cosmetic or food sector. A practically problem-free form of application is that of emulsions containing emulsifiers which reduce the interfacial surface tension of the fat droplets, resulting in a fine and stable distribution of the fat in the water. [0003] Depending on the field of application, there are emulsions of creamy to emulsion-like consistency in which the amount of emulsifier is 0.5-10% (w / w). The particle size of fat droplets of conventional emulsions depends on many factors, such as fat, emulsifier, applied energy, and it is usually in the three-digit nanometer range (100-1000 nm). [0004] Specific problems an...

Claims

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Application Information

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IPC IPC(8): A61K9/107A61K47/10A61K47/24A23L29/00A23L33/15A23L33/155A61K47/26
CPCA61K47/24A61K47/26A61K9/1075A61K47/10A61P13/00A61K9/107
Inventor 鲁迪·瓦伊达
Owner LIPOID GMBH (DE)
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