Domperidone drip pills and its preparation method

Abstract

A dripping pill of domperidone for treating indigestion, nausea, vomiting, etc is prepared from domperidone and matrix.

Description

technical field [0001] The invention relates to a pharmaceutical composition with gastrointestinal prokinetic effect for treating dyspepsia, abdominal distension, belching, nausea and vomiting, in particular to an oral preparation of the pharmaceutical composition prepared from domperidone. Background technique [0002] Domperidone is a gastric motility and antiemetic drug developed by Janson Company in Belgium. It is used to treat functional, organic and infectious nausea, vomiting and non-ulcer dyspepsia. "Guidelines for Product Development" is a product recommended by the relevant state departments to concentrate on R&D and localization. The drug was first launched in Belgium in 1978 and has been successively launched in Germany, Italy, Britain, Japan, France and other countries, and has been widely used in countries all over the world. my country introduced this product in 1986, and Xi'an Janssen Company exclusively imported raw materials to produce preparations and sel...

AI Technical Summary

Problems solved by technology

[0004] The application number is that the Chinese invention patent of 200310100909.6 discloses a kind of domperidone dropping pills, but the domperidone dropping pills prepared according to the disclosed preparation method has a low qualified product rate of roundness rate in industrial production, and the weight difference of pills is also large. It is quite different from the quality index of the dripping pill preparation stipulated in the national drug standard. Such a product seriously affects the accuracy of the dosage in use, and also reduces the pass rate of the product in production, increasing the production cost. Thereby indirectly increasing the cost of medication for patients, thus making its practicability also decrease thereupon