52results about How to "Little difference in pellet weight" patented technology

The invention pertains to the technical field of medicine preparation and relates to a vibration-crushing micro-pill machine which comprises a liquid storage pot, a pill dripping system, a cooling circulation device, a micro-pill collecting machine and a control circuit, wherein the pill dripping system comprises a dropper, a jet hole, a vibration exciter and a gear pump. The dropper is connectedwith the vibration exciter by a rigid connecting rod. The lower part of the dropper is provided with one or more jet holes, the upper part of which is a liquid inlet and the lower part thereof is a nozzle. The dropper is connected with an electric valve at the lower part of the liquid storage pot by pipes on which the gear pump is arranged. The side wall of the dropper is provided with two insertion holes in which a heater and a temperature sensor respectively connected with the control circuit are arranged. The control circuit controls the make-and-break of the heater according to the detected temperature of the temperature sensor. The cooling circulation device comprises a condensation column, a stirring device, a filter, a cooling cylinder, a cooling pump and an electromagnetic pump. The vibration-crushing micro-pill machine has the advantages of chance of batch production of micro-pills, high production efficiency, simple equipment structure and convenient control.

The invention relates to a method using the 3D printing technology to prepare dropping pills. The method using the 3D printing technology to prepare the dropping pills comprises the steps of (1) using polyethylene glycol and the like as base materials, carrying out heating melting, (2) adding prescription drugs at the specified temperature, carrying out mixing, even stir and freeze drying to obtain solid powder, carrying out sieving on the solid powder, and (3) placing the solid powder into a powder box of a 3D printer, and preparing the dropping pills through electronic drafting, remote data transmission and laser scanning printing. According to the method using the 3D printing technology to prepare the dropping pills, due to the facts that through a series of technologies such as the electronic design technology, the remote data transmission technology, the laser scanning technology and the raw material and auxiliary material melting technology, the specific drug powder materials are melted, and electronic model graphs are changed into the real dropping pills according to designed indications, the advantages of the dropping method of preparing the dropping pills are kept, and the defects that due to the influence of the factors such as physical properties of liquid medicine, droppers and cooling liquid, pill weights are different, the roundness of pills is difficult to control, the percent of pass is low, and specially-shaped dropping pills cannot be easily prepared when the dropping method is used for preparation are overcome.

The invention discloses an antivirus drug compound and particularly relates to an oral pharmaceutical preparation adopting famciclovir as the ingredient and being prepared jointly with the medicinal carrier used as the stroma. The antivirus drug compound aims to supplement the deficiency of the prior antivirus oral pharmaceutical preparation and provide a sustained-release famciclovir dropping pill which has high bioavailability, fast effect, high drug content, low frequency of drug taking, full release, convenient drug taking, low cost and absence of contamination during the production. The sustained-release famciclovir dropping pill adopts famciclovir as the ingredient and is prepared jointly with the medicinal carriers of mixing hydrophilic frame ingredients and hydrophobic frame ingredients as the stroma.

The present invention discloses an oral Chinese medicine preparation-Shenqi Xiaoke dripping pills with the functions of supplementing qi and nourishing yin for effectively curing diabetes with obvious therapeutic effect. It is made up by using 13 Chinese medicinal materials of ginseng, astragalus root and others through a certain preparation process.

The present invention discloses a kind of orally taken medicine preparation for treating disease caused by exogenous wind and cold, fever, aversion to cold, headache, etc., and is especially Zhengchaihuyin dripping pill with the extract of traditional Zhengchaihuyin recipe and possessing antiviral and antibacterial effect. The Zhengchaihuyin dripping pill of the present invention has high bioavailability, fast medicine release, quick acting, less toxic side effect, pollution-free production process and low cost. The Zhengchaihuyin dripping pill of the present invention is prepared based on traditional recipe.

A Chinese medicine 'Tongmailing dripping pill' for treating cardiovasular disease is prepared from 8 Chinese-medicinal materials including red sage root, safflower, rehmannia root, Chuan-xiong rhizome, etc. Its preparing process is also disclosed.

The invention discloses a drug combination oral pill preparation which takes Ambroxol hydrochloride and Clenbuterol hydrochloride as drug active ingredients and is used for relieving cough, dissolving phlegm and relieving asthma. The invention aims at overcoming the defects of the present therapeutic drug preparation for relieving cough, dissolving phlegm and relieving asthma and providing the drug combination preparation, namely, a compound Ambroxol sustained-release pill preparation which is characterized by high bioavailability, rapid effect, less times of medicine taking for patients, long acting time, less toxic and side effect and convenient application and carrying for patients and medical workers. The compound Ambroxol sustained-release pill related by the invention uses Ambroxol hydrochloride and Clenbuterol hydrochloride as drug active ingredients and is prepared by mixing the active ingredients with a hydrophilic framework material and a hydrophobic framework material that are used as substrate.

The invention discloses a medicament for treating cardiovascular and cerebrovascular diseases, which is a dripping pill prepared from effective dose of base material and the following raw material effective composition (by weight portion): herba erigerontis 500g, orange-jasmine 500g, ginkgo leaves 500g, and notoginseng 200g. The medicament has the advantages of rapid dissolving rate, complete absorption and high biological availability.

The invention discloses a preparation method of saffron extract drop pills which comprises the following steps, melting safflower extract, water and base material polyethylene glycol (PEG), dropping into cooling material, removing cooling material on the surface of the drop pills, finally drying to obtain the end product.

The present invention discloses one kind of orally taken antifungal medicine composition, and aims at providing one kind of antifungal itraconazole dripping pill with high bioavailability, fast medicine release, fast acting, high medicine content, easy taking, low cost and production process without pollution. The itraconazole dripping pill is prepared with itraconazole as medicine material and medicine carrier as matrix.

The invention belongs to the field of medicine preparation, and particularly discloses a preparation method for a condensed pill of traditional Chinese medicines. The preparation method comprises thefollowing steps: preparing particles from a part of a medicinal material extract and fine medicinal material powder, carrying out pressing to from a pill mold, adopting the pill mold as a base pill, and rounding the remaining prescription amounts of the medicinal material extract and the fine medicinal material powder and a proper amount of an excipient to form the pill. According to the preparation method disclosed by the invention, effective components can be reserved to the greatest extent; the preparation method well solves problems in proportioning stability of the extract and the medicinal powder; prepared condensed pills are small in pill weight difference, accurate in dosage, shortened in dissolution and dispersion time limit, good in absorption, stable and controllable in qualityand improved in curative effect; a production period is shortened; process is simple; a production environmental is good in sanitation condition; labor intensity is reduced; various quality indexes are obviously improved; and good social and economic benefits are obtained.

A dripping pill of nitrendipine for treating hypertension is proportionally prepared from nitrendipine and the matrix chosen from polyethanediol 4000, 6000 or 10000, stearic acid, sodium stearate, poloxamer, glycerin gelatin, monoglyceride stearate, shellac and polyoxyvinyl monostearate through thermally fusing said matrix, mixing it with nitrendipine, dripping in condensing agent, removing the condensing agent from their surface, drying in air and packing.

The rabdosia dripping pill consists of rabdosia extract as the active component and one or several kinds of matrix, and through mixing and other steps. The rabdosia dripping pill has the functions of dispelling wind evil, clearing away heat, eliminating toxic matter, eliminating swelling, relieving pain, etc. and is used in treating acute and chronic tonsillitis, pharyngitis, laryngitis, stomatitis and other diseases. It has fast acting, small dosage, no toxicity, no side effect, and other features.

The invention discloses an application of cinnamon oil for preparing a medicine for treating arrhythmia and the medicine prepared by the cinnamon oil. The main component cinnamyl aldehyde in the cinnamon oil can improve the perfusion pressure of the coronary artery and the cerebral artery correspondingly to accelerate the collateral circulation of the cardiac muscle to be opened, so that blood supply of the cardiac muscle is changed to protect the cardiac muscle, therefore, the cinnamon oil has the effect of preventing arrhythmia. The cinnamon oil dropping pill provided by the invention has the effect of preventing arrhythmia, improving myocardial ischemia and resisting hypoxia, and the cinnamon oil can be applied to preparing the medicine for treating arrhythmia.

The invention relates to a carbidopa-levedopa sustained-release dropping pill for the treatment of Parkinson's disease and a preparation method thereof. The invention aims to solve the insufficiencies of an oral preparation, and provides a carbidopa-levedopa sustained-release dropping pill, which has advantages of high bioavailability, rapid effectiveness, long action time, low frequency of drug taking, convenient administration, little toxic or side effect, convenient storage and transportation, and suitability for oral administration, and the preparation method thereof.

The invention relates to a troxerutin sustained-release drop pill for the treatment of hemiplegia, aphasia, arteriosclerosis, central retinitis, thrombophlebitis, varicose veins and other symptoms caused by cerebral thrombosis and cerebral embolism, as well as a preparation method thereof. The invention aims at utilizing the sustained-release pharmaceutical technology to make up for the shortcomings of the prior art and providing the troxerutin sustained-release drop pill with high bioavailability, few administration times, long-term effect, no toxicity, no side effects and convenient usage and carrying, as well as the preparation method thereof. The troxerutin is taken as raw material, a hydrophilic skeleton material and a hydrophobic skeleton material are added according to certain weight percentages to be taken as matrixes and evenly mixed, the mixed materials are heated till melting, evenly stirred and arranged in a special pill dropping machine, and then dropped into condensate liquid at appropriate speed for preparation.

A dripping pill of ginsenoside is prepared from ginsenoside through proportional adding polyoxyvinyl monostearate, mixing, heating for fusing, stirring, and dripping in condensing liquid.

A dripping pill of pravastatin is prepared from pravastatin through proportional adding polyoxyvinyl monostearate, mixing, heating for fusing, stirring, and dripping in condensing liquid.

The invention relates to a sustained-release drug used for treating bronchitis, asthma and lung diseases as well as the preparation method thereof, and aims to supplement the deficiencies that existing tablets, capsules and oral formulations have short acting time, unsteady plasma concentration and deficient preparation method and provide a sustained-release ambroxol hydrochloride dropping pill which has good substance dispersion state, long acting time and high bioavailability. The sustained-release ambroxol hydrochloride dropping pill is prepared by adopting ambroxol hydrochloride as the ingredient, adding in hydrophilic frame ingredients and hydrophobic frame ingredients as the stroma according to a definite proportion and mixing well, heating the mixture to meltdown and mixing well, putting the melted mixture into a dropping pill machine and trickling the melted mixture into a condensing agent to be cooled off.

The invention provides a Gongyankang dropping pill preparation with fast collapse, fast drug release and high bioavailability and a preparation method thereof, and the dropping pill can be prepared into ordinary dropping pill preparation, sustained-release dropping pill preparation, enteric-coated dropping pill preparation, coated dropping pill preparation, and the like. The Gongyankang dropping pill preparation is prepared by taking Chinese angelica, red paeony root, dahurian patrinia herb, nutgrass galingale rhizome (vinegar prepared), baked ginger, hiraute shiny bugleweed herb, Szechuan lovage rhizome, safflower, Chinese thorowax root, seaweed, plantain seed (stir-fried with salt) and yanhusuo as pharmaceutical raw materials, and the Gongyankang dropping pill preparation is prepared into the dropping pill to achieve the purposes of improving bioavailability, more fully playing the efficacies of the medicines, reducing adverse reactions, and the like. Therefore, the Gongyankang dropping pill which has high content of active ingredients, great roundness, rapid dissolution, small weight difference of the pills, hardness that is in line with the requirements of the dropping pill preparation and reliable quality.

The invention relates to a traditional Chinese medicine formulation mirabilitum praeparatum throat-soothing dropping pill and a preparation method thereof. The traditional Chinese medicine formulation mirabilitum praeparatum throat-soothing dropping pill comprises the following active pharmaceutical components in parts by weight: 20-80 parts of mirabilitum praeparatum, 0.5-5 parts of borneol, 1-5 parts of dementholized peppermint oil and 1-6 parts of menthol; an auxiliary material comprises the following components in parts by weight: 100-350 parts of polyethylene glycol-4000 and 1-6 parts of steviosin. The invention also relates to the preparation method of the mirabilitum praeparatum throat-soothing dropping pill. The mirabilitum praeparatum throat-soothing dropping pill disclosed by the invention is relatively high in heat stability by selecting the steviosin as a flavoring agent, and can not be decomposed by being heated for a long time, thereby solving the problem of instable heat of aspartame in the prior art; meanwhile, the preparation method disclosed by the invention solves the problem that a dropper is easy to adhere in a dropping process by regulating the matrix ratio, therefore, the preparation process is more suitable for large-scale industrialized production and ensures the smoothness of a production process.

The invention relates to an antiulcer drug Lansoprazole sustained-release preparation and a preparation method thereof; the invention aims at overcoming the defect of oral preparation and providing a Lansoprazole sustained-release pill for oral administration which is characterized by high bioavailability, rapid effect, long acting time, less times of oral administration, convenient application, less toxic and side effect and convenient storage and transportation, and the preparation method thereof. In particular, the Lansoprazole sustained-release pill is added with a stabilizing agent, Vitamin E, which prevents the occurrence of pill aging and leads the pill to be more stable.

A Chinese medicine in the form of dripping pill for treating hepatism is prepared from stem and leaf of ginseng and bupleurum root through extracting ginsenoside and saikoside. Its preparing process is also disclosed.

The invention discloses a medicinal oral preparation, having the functions of dispersing pathogenic wind, detoxification, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, no contamination in production. The preparation is prepared through the conventional drop pill making process.

A dripping pill of domperidone for treating indigestion, nausea, vomiting, etc is prepared from domperidone and matrix.

The invention relates to a dihydrocodeine tartrate sustained-release dropping pill for treatment of moderate pain and a preparation method thereof. The invention aims to solve the defects of an oral preparation, and provides the dihydrocodeine tartrate sustained-release dropping pill, which has advantages of high bioavailability, rapid effectiveness, long action time, low frequency of drug taking, convenient administration, little toxic or side effect, convenient storage and transportation, and suitability for oral administration, and the preparation method thereof.

The invention belongs to the technical field of pharmacy, and in particular relates to a glipizide sustained-release dropping pill for treating diabetes and a preparation method thereof. Based on glipizide sustained-release dropping pill, the drug provided by the invention is prepared by existing preparation technology of dropping pill. Compared to the prior art, the invention is the supplement for the defects of existing drug form production, and provides a drug, which has advantages of high bioavailability, rapid effectiveness, long-acting effect, little toxic or side effect, high drug content, small and accurate dosage, convenient usage, low price and convenience for carrying.

The invention discloses a medicinal dripping pill for treating osteoporosis, which consists of red infested rice, fortune drynaria rhizome, epimedium herb and polyethylene glycol. Compared with the prior art, the dripping pill has the characteristics of high bioavailability, quick medicament release, quick response, high medicament content, accurate measurement, convenience of taking, low price, no pollution during the production and the like.