Ginseng bupleurum drop pill for treating liver disease and its preparation method
A technology of Kangdi Pills and Liver Diseases, which is applied in the field of oral preparations of pharmaceutical compositions, to achieve the effects of improving bioavailability, rapid onset of action, and light weight
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[0065] Now with several groups of specific examples, the preparation method of the Shenchai Gankang dripping pills of the present invention will be further described.
[0066] Group 1: Tests with a single matrix
[0067] 1. The Bupleurum extract containing saikosaponin—the Bupleurum extract containing saikosaponin obtained by [preparation method] 1;
[0068] 2. Total saponins from ginseng stems and leaves - commercially available finished products;
[0069] 3. Substrate - polyethylene glycol 1500 , polyethylene glycol 2000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate and other pharmaceutically acceptable carriers;
[0070] 4. Proportion—taking g or kg as the unit, by weight, total saponins from stems and leaves of ginseng:bupleurum radiata extract=2.6:2.3; drug mixture:substrate=1:1˜1:5.
[0071] 5. Prepare according to the proc...
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