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Medicinal dripping pill for treating osteoporosis

A technology for osteoporosis and drugs, applied in the field of drug drop pills for the treatment of osteoporosis, can solve the problems of increasing the risk of breast cancer and endometrial cancer, and achieve improved bioavailability, faster dissolution and absorption , quick effect

Active Publication Date: 2011-07-20
BEIJING WBL PEKING UNIV BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current clinical treatment is mainly estrogen replacement therapy, but long-term application of estrogen may increase the risk of breast cancer and endometrial cancer

Method used

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  • Medicinal dripping pill for treating osteoporosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Red yeast rice 3kg Drynaria rhizome 3kg Epimedium 3kg

[0050] The above-mentioned medicines are respectively made into water extract dry cream according to the conventional process, and mixed to obtain the composition intermediate; according to the weight ratio, the composition intermediate: PEG4000=1: 3.2 ratio is added PEG4000, and the preparation method of the dropping pill is: After the polyethylene glycol is heated and melted, add the composition intermediate, mix well, and keep warm at 75±2°C; drop it into the coolant with a dropping pill machine, where the temperature of the coolant is 20±2°C, and take out the dropping pill after molding , remove the coolant on the surface, and pack it.

Embodiment 2

[0052] Red Yeast 2kg Drynaria 4kg Epimedium 2kg

[0053] The above-mentioned medicines are respectively made into alcohol extract dry cream according to the conventional process, and mixed to obtain the composition intermediate; according to the weight ratio, the composition intermediate: PEG4000=1: 4.5 is added in the ratio of PEG4000, and the preparation method of the dropping pill is: After ethylene glycol is heated and melted, add the composition intermediate, mix evenly, and keep warm at 75±2°C; drop it into the coolant with a dropping pill machine, where the temperature of the coolant is 20±2°C, take out the dropping pill after molding, Remove the coolant on the surface and pack it.

Embodiment 3

[0055] Red Yeast 4kg Drynaria 2kg Epimedium 4kg

[0056] The above-mentioned drugs are jointly extracted according to the conventional process to make a dry paste of the extract obtained by water extraction and alcohol precipitation through a macroporous resin adsorption column, and mixed to obtain a composition intermediate; according to the weight ratio, PEG4000 is added in a ratio of composition intermediate: PEG4000=1:2.5 , the preparation method of dropping pills is: after heating and melting polyethylene glycol, add the composition intermediate, mix well, keep warm at 75±2°C; drop into the coolant with a dropping pill machine, and the temperature of the coolant is 20±2°C 2°C, after molding, take out the dropping pills, remove the coolant on the surface, and pack them.

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Abstract

The invention discloses a medicinal dripping pill for treating osteoporosis, which consists of red infested rice, fortune drynaria rhizome, epimedium herb and polyethylene glycol. Compared with the prior art, the dripping pill has the characteristics of high bioavailability, quick medicament release, quick response, high medicament content, accurate measurement, convenience of taking, low price, no pollution during the production and the like.

Description

technical field [0001] The invention relates to a medicine drop pill, in particular to a medicine drop pill for treating osteoporosis. Background technique [0002] Osteoporosis has become a common disease in menopausal and postmenopausal women in recent years. Osteoporosis is a physiological degenerative disease that does great damage to human health and has a high clinical incidence. Clinically, it is mostly low back pain, fracture, old fracture of unknown cause or hyperplastic spondylitis, and the age is mostly between 35-55. Osteoporosis is a systemic osteopenia and changes in bone tissue structure related to endocrine function, accompanied by bone fragility and a disease that easily leads to fractures. It often brings inconvenience and pain to the lives of middle-aged and elderly people, and even loses their lives due to fractures, which increases the burden on families and society. With the aging of society, the prevention and treatment of osteoporosis has become an ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/296A61K47/34A61K9/20A61P19/10A61K47/10
Inventor 段震文郭树仁
Owner BEIJING WBL PEKING UNIV BIOTECH
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